Funding Opportunities - University of Houston
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Funding Opportunities

Expand the boxes below to see current funding opportunities by agency. This list has been curated specifically to the interests of NSM and is typically updated twice a month. The NEW tag indicates opportunities most recently added.

NEW FY24 Peer Reviewed Medical Research Program (PRMRP)
Sponsored by: Dept. of the Army (USAMRAA) Congressionally Directed Medical Research Programs
Programs of interest:
Discovery Award (DA): Supports innovative, untested, non-incremental, high-risk/potentially high-reward research that will provide new insights, paradigms, technologies or applications. Not intended to support the logical progression of an already established line of questioning. Postdocs and above are eligible to be PI.
Deadline: LOI: May 6, 2024; Full proposal: May 23, 2024

Investigator-Initiated Research Award (IIRA): Supports research that will make an important
contribution toward research, patient care and/or quality of life for a disease of condition in the Topic Area(s) of interest. Assistant Professor level or above are eligible to be PI.
Deadline: LOI: May 6, 2024; Full proposal: May 23, 2024

Impact Award (IPA): Supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research, and insights from real-world environment to foster clinical applicability in the Topic Area(s) of interest. Assistant Professor level or above are eligible to be PI.
Deadline: LOI: May 13, 2024; Full proposal: June 6, 2024

Technology/Therapeutic Development Award (TTDA): Supports the translation of promising preclinical
findings into products for clinical applications including prevention, detection, diagnosis, treatment, and/or quality of life. Supports product-oriented projects (e.g., device, drug, clinical guidelines). The product(s) to be
developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product. Assistant Professor level or above are eligible to be PI.
Deadline: LOI: May 13, 2024; Full proposal: June 6, 2024

NEW FY25 Department of Defense Multidisciplinary Research Program of the University Research Initiative (MURI)
Solicitation: N0001424SF002
Sponsored by: Office of Naval Research (ONR)
Deadline: White papers: May 17, 2024; Full applications: Sep 06, 2024
Description: The MURI program supports basic research in science and engineering at U.S. institutions of higher education that is of potential interest to DoD. The program is focused on multidisciplinary research efforts where more than one traditional discipline interacts to provide rapid advances in scientific areas of interest to the DoD.

NEW Air Force Fiscal Year 2025 Young Investigator Program (YIP)
Solicitation: FOAAFRLAFOSR20240004
Sponsored by: Air Force Office of Scientific Research (AFOSR)
Deadline: White papers: Apr 22, 2024; Full proposals: Jun 21, 2024
Description: The Fiscal Year 2025 Air Force Young Investigator Research Program (YIP) intends to support individual early in career scientists and engineers who have received PhD or equivalent degrees by 01 April 2017 or later showing exceptional ability and promise for conducting basic research. The program objective is to foster creative basic research in science and engineering; enhance early career development of outstanding young investigators; and increase opportunities for the young investigator to recognize the Air Force and Space Force mission and related challenges in science and engineering.

NEW ONR Young Investigator Program
Solicitation: N0001424SF004
Sponsored by: Office of Naval Research (ONR)
Deadline: Apr 30, 2024
Description: ONR's Young Investigator Program seeks to identify and support academic scientists and engineers who are in their first or second full-time tenure-track or tenure-track-equivalent academic appointment, who have received their PhD or equivalent degree on or after 01 January 2017, and who show exceptional promise for doing creative research. The objectives of this program are to attract outstanding faculty members of U.S. Institutions of Higher Education to the Department of the Navy's Science and Technology (S&T) research program, to support their research, and to encourage their teaching and research careers. Individuals who are holding U.S. non-profit equivalent positions are also encouraged to apply. Proposals addressing research areas which are of interest to ONR Program Officers will be considered.

NEW NRL Long Range Broad Agency Announcement (BAA) for Basic and Applied Research
Solicitation: N00173-24-S-BA01
Sponsored by: Naval Research Laboratory
Deadline: Dec 31, 2024
Description: The Naval Research Laboratory (NRL) is the Navy's corporate laboratory. NRL conducts basic and applied research for the Navy in a variety of scientific and technical disciplines. The research conducted at NRL is a broadly based multidisciplinary program of scientific research and advanced technological development directed toward maritime applications of new and improved materials, techniques, equipment, systems and ocean, atmospheric, and space sciences and related technologies. Although NRL conducts most of its research programs within NRL facilities and associated warfare centers, NRL intends to fund research conducted with educational facilities and industry partners which are related to specific topics included in this BAA announcement.

FY24 Department of Navy (DON) Science, Technology, Engineering, and Mathematics (STEM) Education and Workforce Program
Solicitation: N0001424SF003
Sponsored by: Office of Naval Research (ONR)
Deadline: Aug 30, 2024
Description: The Office of Naval Research (ONR) is interested in receiving a broad range of proposals for augmenting existing and/or developing innovative solutions that directly maintain, and/or cultivate a diverse, world-class Science, Technology, Engineering, and Mathematics (STEM) workforce to maintain the U.S. Navy and Marine Corps’ technological superiority. The goal of proposed efforts must provide solutions that establish, build, and/or maintain STEM educational pathways of U.S. citizens directly relevant to the needs of Department of Navy’s (DON) current and future workforce. As the capacity of the DON Science and Technology (S&T) workforce is interconnected with the STEM education system, DON recognizes the need to support efforts that can jointly improve STEM student outcomes and align educational and outreach efforts with Naval S&T current and future workforce needs. This announcement explicitly encourages programs that improve the capacity of education systems and communities to create impactful STEM educational experiences for students of all ages and the naval related workforce. Programs must aim to increase engagement in naval relevant STEM, and enhance the corresponding skills, knowledge, and abilities of participants. ONR encourages applicants to utilize current STEM educational research for informing program design and advancing STEM careers and opportunities of naval relevance.

Young Faculty Award (YFA)
Solicitation: 2025 DARPA YFA
Sponsored by: Defense Advanced Research Projects Agency (DARPA), Defense Sciences Office (DSO)
Deadline: (expected) LOIs: December 2024; Proposals: February 2025
Description: The YFA aims to identify and engage rising stars in junior research positions in academia and
equivalent positions at non-profit research institutions, particularly those without prior DARPA
funding, to expose them to Department of Defense (DoD) needs and DARPA’s mission to create
and prevent technological surprise. The YFA program will provide high-impact funding to elite
researchers early in their careers to develop innovative new research that enables transformative
DoD capabilities. Ultimately, the YFA program is developing the next generations of researchers
focused on national security issues.

ARO - Defense University Research Instrumentation Program (DURIP)
Solicitation: 2026 ARO DURIP
Sponsored by: Dept of the Army -- Materiel Command
Deadline: (expected) February 2025
Description: The Department of Defense (DoD) announces the Fiscal Year 2025 Defense University Research Instrumentation Program (DURIP). DURIP is designed to improve the capabilities of accredited United States (U.S.) institutions of higher education to conduct research and to educate scientists and engineers in areas important to national defense, by providing funds for the acquisition of research equipment or instrumentation. For-profit organizations are not eligible for DURIP funding.

AFOSR - Defense University Research Instrumentation Program (DURIP)
Solicitation: 2026 AFOSR DURIP
Sponsored by: Air Force Office of Scientific Research
Deadline: (expected) February 2025
Description: The Department of Defense (DoD) announces the Fiscal Year 2025 Defense University Research Instrumentation Program (DURIP). DURIP is designed to improve the capabilities of accredited United States (U.S.) institutions of higher education to conduct research and to educate scientists and engineers in areas important to national defense, by providing funds for the acquisition of research equipment or instrumentation. For-profit organizations are not eligible for DURIP funding.

ONR - Defense University Research Instrumentation Program (DURIP)
Solicitation: 2026 ONR DURIP
Sponsored by: Office of Naval Research
Deadline: (expected) February 2025
Description: The Department of Defense (DoD) announces the Fiscal Year 2025 Defense University Research Instrumentation Program (DURIP). DURIP is designed to improve the capabilities of accredited United States (U.S.) institutions of higher education to conduct research and to educate scientists and engineers in areas important to national defense, by providing funds for the acquisition of research equipment or instrumentation. For-profit organizations are not eligible for DURIP funding.

Research and Education Program for Historically Black Colleges and Universities and Minority-Serving Institutions (HBCU/MI)
Solicitation: W911NF-19-S-0013
Sponsored by: Dept of the Army -- Materiel Command
Deadline: April 30, 2024 (renews annually)
Description: Projects proposed for funding under this FOA include all scientific study and experimentation directed toward increasing fundamental knowledge and understanding in those fields of the physical, engineering, environmental, life sciences, and information sciences related to long-term national security needs. PIs are encouraged to consider innovative approaches for their research projects with a view toward enhancing the ability of their institution to develop stronger science and engineering programs that will enable the institution to participate more competitively in a variety of defense research programs, attract and retain good students by exposing them to state-of-the-art research, and encourage them to pursue careers in STEM disciplines.

Information Innovation Office (I2O) Office-wide
Solicitation: HR001123S0003
Sponsored by: Defense Advanced Research Projects Agency (DARPA), Information Innovation Office (I2O)
Deadline: Oct 29, 2024
Description: The mission of the Information Innovation Office (I2O) is to ensure enduring advantage for the United States and its allies across a broad range of information technologies through the advancement of core technical foundations and the design of novel application concepts based on these foundations. I2O’s core technical work ranges from artificial intelligence and data analysis to secure engineering and formal methods. Building on its core technical work, I2O programs also focus on overcoming technical challenges in bringing these technologies to the mission, addressing topics such as network security, cyber and multi-domain operations, human-system interaction, and assured autonomy. I2O programs are organized into four thrust areas: Proficient artificial intelligence (AI); Advantage in cyber operations; Confidence in the information domain; and Resilient, adaptable, and secure systems.

ERDC Broad Agency Announcement
Solicitation: W912HZ-24-BAA-01
Sponsored by: Dept. of the Army -- Corps of Engineers
Deadline: Dec 31, 2024 (renewed annually)
Description: The U.S. Army Engineer Research and Development Center (ERDC) has issued a Broad Agency Announcement (BAA) for various research and development topic areas. The ERDC consists of the Coastal and Hydraulics Lab (CHL), the Geotechnical and Structures Lab (GSL), the Reachback Operations Center (UROC), the Environmental Lab (EL) and the Information Technology Lab (ITL) in Vicksburg, Mississippi, the Cold Regions Research and Engineering Lab (CRREL) in Hanover, New Hampshire, the Construction Engineering Research Lab (CERL) in Champaign, Illinois, and the Geospatial Research Laboratory (GRL) in Alexandria, Virginia. The ERDC is responsible for conducting research in the broad fields of hydraulics, dredging, coastal engineering, instrumentation, oceanography, remote sensing, geotechnical engineering, earthquake engineering, soil effects, vehicle mobility, self-contained munitions, military engineering, geophysics, pavements, protective structures, aquatic plants, water quality, dredged material, treatment of hazardous waste, wetlands, physical/mechanical/ chemical properties of snow and other frozen precipitation, infrastructure and environmental issues for installations, computer science, telecommunications management, energy, facilities maintenance, materials and structures, engineering processes, environmental processes, land and heritage conservation, and ecological processes.

EcoSystemic (AIE)
Solicitation: DARPA-PA-20-02
Sponsored by: Dept. of Defense-DARPA
Deadline: Continuously accepted through July 31, 2026
Description: The Defense Advanced Research Projects Agency (DARPA) is issuing an Artificial Intelligence Exploration (AIE) Opportunity, inviting submissions of innovative basic research concepts in the technical domain of consistency in federated data stores. The Ensuring Consistency of Systemic Information (ECoSystemic) Opportunity aims to develop innovative techniques to improve the mutual consistency of federated backups, together with processes for recovering a distributed system of potentially global scale promptly to a functional and mutually consistent restored state. Robust recovery of information systems has broad applicability in both military and commercial domains.

Artificial Intelligence Integration Center (AI2C) - Transformative Artificial Intelligence Research and Applications Broad Agency Announcement (BAA)
Sponsored by: Dept. of the Army
Deadline: Continuously accepted through July 31, 2026
Description: The Army Artificial Intelligence Integration Center (AI2C) is seeking artificial intelligence research and development whitepapers and proposals in support of new technologies and translational research-based approaches that support the identification, alignment, and exploitation of basic, applied, and advanced research and technology.

NEW FY 2024 Funding for Accelerated, Inclusive Research (FAIR)
Solicitation Number: DE-FOA-0003207
Deadline: July 16, 2024
Description: FAIR is focused on building research capacity at academic institutions that have been historically underrepresented in the SC portfolio. Capacity building is interpreted broadly to include both personnel expertise and infrastructure and is expected to be durable, contributing over time toward sustained research strength at the lead institution. Because collaboration is critical to SC research, relationship building through the partnership is considered a key component of the FAIR program. All applications must be submitted on behalf of a lead institution and include a single partnering team member. The lead institution must be a non-R1 MSI or a non-R1 ERI and the partner must be either a DOE National Laboratory, an SC Scientific User Facility, or an R1 MSI/ERI (UH would be the partner institution).

NEW Advancements in Artificial Intelligence for Science
Solicitation Number: DE-FOA-0003264
Deadline: May 21, 2024
Description: The DOE SC program in Advanced Scientific Computing Research (ASCR) hereby announces its interest in basic computer science and applied mathematics research in the fundamentals of Artificial Intelligence (AI) for science. Specifically, advancements in this area are sought that can enable the development of (1) Foundation models for computational science; (2) Automated scientific workflows and laboratories; (3) Scientific programming and scientific-knowledge-management systems; (4) Federated and privacy-preserving training for foundation and other AI models for science; and (5) Energy-efficient AI algorithms and hardware for science. The development of new AI techniques applicable to multiple scientific domains can accelerate progress, increase transparency, and open new areas of exploration across the scientific enterprise.

Spurring Projects to Advance Energy Research and Knowledge Swiftly (SPARKS) (DOE ARPA-E)
Solicitation Number: DE-FOA-0003164
Deadline: Proposals are accepted at any time
Description: This program provides a continuing opportunity for the rapid support of early-stage applied research to explore innovative new concepts with the potential for transformational and disruptive changes in energy technology. SPARKS awards are intended to be flexible and may take the form of analyses or exploratory research that provides the agency with useful information for the subsequent development of focused technology programs. SPARKS awards may also support proof-of-concept research to develop a unique technology concept, either in an area not currently supported by the agency or as a potential enhancement to an ongoing focused technology program.

FY2024 Continuation of Solicitation for the Office of Science Financial Assistance Program
Solicitation Number: DE-FOA- 0003177
Deadline: September 30, 2024
Description: The Office of Science hereby announces its continuing interest in receiving grant applications for support of work in the following program areas: Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, Isotope R&D and Production, and Accelerator R&D and Production. There is also an early career track.

NEW Coastal Ecosystems Climate Resilience
Solicitation Number: EPA-G2024-STAR-C1
Deadline: Pre-proposals: May 1, 2024
Description: The U.S. Environmental Protection Agency, as part of its Science to Achieve Results (STAR) program, aims to promote scientific progress towards the understanding of coastal ecosystem resilience by seeking applications proposing research to 1) characterize, quantify, and define indicators or metrics of resilience for various types of coastal ecosystems, especially those ecosystems that have climate mitigation and adaptation and/or blue (ocean-stored) carbon sequestration potential and 2) develop methods and approaches to advance economic valuation of resilience benefits provided by coastal ecosystems.

NEW Research Opportunities in Space and Earth Science (ROSES)-2024
Solicitation Number: NNH24ZDA001N
Deadline: varies by program
Description: ROSES-2024 is an omnibus NASA Research Announcement. It contains over 100 different proposal opportunities. See Table 2: Solicited Research Programs for the full list of opportunities.

NEW Early Stage Innovations
Solicitation Number: NNH24ZTR001N-24ESI-B2
Deadline: Jun 06, 2024
Description: The Space Technology Research Grants (STRG) Program seeks proposals to develop unique, disruptive, or transformational space technologies that have the potential to lead to dramatic improvements at the system level — performance, weight, cost, reliability, operational simplicity, or other figures of merit associated with spaceflight hardware or missions. The projected impact at the system level must be substantial and clearly identified. The solicitation exclusively seeks proposals that are responsive to one of the following two topics: Topic 1 – Computational Materials Engineering for Lunar Metals Welding; Topic 2 – Passive Lunar Dust Control through Advanced Materials and Surface Engineering. NASA anticipates addressing other topics in future ESI Appendix releases.

NEW University Leadership Initiative (ULI)
Solicitation Number: NNH24ZEA001N-ULI
Deadline: Pre-proposals: May 29, 2024
Description: The University Leadership Initiative (ULI) provides the opportunity for university teams to exercise technical and organizational leadership in proposing unique technical challenges in aeronautics, defining multi-disciplinary solutions, establishing peer review mechanisms, and applying innovative teaming strategies to strengthen the research impact. Research proposals are sought in six ULI topic areas that can be found in the program announcement.

ROSES 2023: A.67 Earth Action: Supporting Climate Resilient Communities
Solicitation Number: NNH23ZDA001N-CRC
Deadline: May 03, 2024
Description: The NASA Earth Science Division (ESD) solicits proposals that support communities in
building their resilience to climate impacts through the application of NASA Earth
observations. The focus of proposals must be on informing decisions that enhance
community-level resilience to episodic and chronic climate stressors.

Solicitation Number: NNH24ZHA003C
Deadline: Sep 30, 2026
Description: The NASA OSTEM MUREP Program solicits proposals from 4-year colleges/universities designated by the U.S. Department of Education as MSIs for the MUREP Institutional Research Opportunity (MIRO) activity. MIRO develops significant scientific, engineering, and/or technology research centers. The purpose of MIRO is to strengthen and develop the research capacity and infrastructure of MSIs in areas of strategic importance and value to NASA’s mission and priorities. MIRO awards promote STEM literacy and enhance and sustain the capability of institutions to perform NASA-related research and education. Additionally, MIRO strengthens student participation in research at MSIs in order to develop and diversify the next generation of the STEM workforce. MIRO awards directly support research pertinent to NASA’s five Mission Directorates (MDs) – Aeronautics Research, Exploration Systems Development, Space Operations, Science, and Space Technology.

NEW Probability
Solicitation Number: PD-18-1263
Deadline: September 17, 2024
Description: The Probability Program supports research on the theory and applications of probability. Subfields include discrete probability, stochastic processes, limit theory, interacting particle systems, stochastic differential and partial differential equations, and Markov processes. Research in probability which involves applications to other areas of science and engineering is especially encouraged.

NEW Mathematical Foundations of Digital Twins
Solicitation Number: NSF 24-559
Deadline: June 20, 2024; March 17, 2025; March 15, Annually Thereafter
Description: The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the Air Force Office of Scientific Research (AFOSR) plan to jointly support foundational mathematical and statistical research on Digital Twins in applied sciences. Recent years have witnessed a significant increase in the demand and interest in applications that involve collaborative teams developing and analyzing Digital Twins to support decision making in various fields, including science, engineering, medicine, urban planning, and more. Both agencies recognize the need to promote research aiming to stimulate an interplay between mathematics/statistics/computation and practical applications in the realm of Digital Twins. This program encourages new collaborative efforts within the realm of Digital Twins, aiming at stimulating fundamental research innovation, pushing, and expanding the boundaries of knowledge, and exploring new frontiers in mathematics and computation for Digital Twin development, and its applications. By leveraging this synergy, the program aims to harness science, technology, and innovation to address some of our Society's most pressing challenges.

NEW Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation
Solicitation Number: NSF 24-561
Deadline: June 21, 2024; May 05, 2025; First Monday in May, Annually Thereafter
Description: The Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation (FDT-BioTech) program supports inherently interdisciplinary research projects that underpin the mathematical and engineering foundations behind the development and use of digital twins and synthetic data in biomedical and healthcare applications, with a particular focus on digital, in silico models used in the evaluation of medical devices and the relevance of the developed models in addressing current and emerging challenges affecting the development and assessment of biomedical technologies. The goal of the FDT-BioTech initiative is to catalyze biomedical technological innovation through new foundational development of methods and algorithms relevant to digital twins and synthetic humans.

NEW Artificial Intelligence, Formal Methods, and Mathematical Reasoning
Solicitation Number: NSF 24-554
Deadline: June 03, 2024; February 05, 2025; February 05, 2026
Description: The Artificial Intelligence, Formal Methods, and Mathematical Reasoning (AIMing) program seeks to support research at the interface of innovative computational and artificial intelligence (AI) technologies and new strategies/technologies in mathematical reasoning to automate knowledge discovery. Mathematical reasoning is a central ability of human intelligence that plays an important role in knowledge discovery. In the last decades, both the mathematics and computer science communities have contributed to research in machine-assisted mathematical reasoning, encompassing conjecture, proof, and verification. This has been in the form of both formal methods and interactive theorem provers, as well as using techniques from artificial intelligence. Recent technological advances have led to a surge of interest in machine-assisted mathematical reasoning from the mathematical sciences, formal methods, and AI communities. In turn, advances in this field have potential impact on research in AI.

NEW Improving Undergraduate STEM Education: Computing in Undergraduate Education
Solicitation Number: NSF 24-553
Deadline: May 30, 2024; April 29, 2025; Last Tuesday in April, Annually Thereafter
Description: The Improving Undergraduate STEM Education: Computing in Undergraduate Education (IUSE: CUE) program aims to better prepare a wider, more diverse range of students to collaboratively use computation across a range of contexts and challenging problems. With this solicitation, the National Science Foundation focuses on re-envisioning how to teach computing effectively to a broad group of students, in a scalable manner, with an emphasis on broadening participation of groups who are underrepresented and underserved by traditional computing courses and careers.

Partnerships in Astronomy & Astrophysics Research and Education (PAARE)
Solicitation Number: NSF 24-516
Deadline: February 18, 2025; February 15, Annually Thereafter
Description: The objective of PAARE is to improve the quality and environment of astronomy and astrophysics research and education by stimulating the development of formal, long-term partnerships that provide authentic pathways into the research enterprise and broaden participation in astronomy by encouraging proposals from the full spectrum of talent across society to include individuals from groups that have been historically underrepresented. Partnerships must substantially involve institutions seeking to create opportunities for student and faculty research that will increase the recruitment, retention, and success of these individuals. It is expected that the partnerships will build or strengthen research capacity, as well as foster a diverse, inclusive, and equitable environment for astronomy and astrophysics research and education at the partnering institutions.

Partnerships for Research Innovation in the Mathematical Sciences (PRIMES)
Solicitation Number: NSF 24-517
Deadline: August 21, 2024; 3rd Wednesday in August, Annually Thereafter; February 12, 2025; 2nd Wednesday in February, Annually Thereafter
Description: The NSF Division of Mathematical Sciences’ Partnerships for Research Innovation in the Mathematical Sciences program aims to enhance partnerships between minority-serving institutions and DMS-supported Mathematical Sciences Research Institutes. The activity seeks to boost the participation of members of groups underrepresented in the mathematical sciences through their increased involvement in research programs at the institutes.

Partnership to Advance Conservation Science and Practice (PACSP)
Solicitation Number: NSF 24-531
Deadline: April 24, 2024; December 19, 2024; 3rd Thursday in December, Annually Thereafter
Description: The objective of the PACSP Program is to support conservation research that investigates organismal biology, ecology, and/or evolution and is designed to contribute to the development and implementation of evidence-based activities and/or technology solutions to advance biodiversity conservation. We seek proposals that involve the implementation of conservation activities based on conservation science principles via academic-conservation organization partnerships. The strongest projects will involve ongoing assessment of biodiversity outcomes, for instance via an adaptive management framework, that inform both scientific understanding and conservation actions. A significant distinction between the PACSP program and other NSF programs is that proposals to this program must make clear and well-defined connections between basic research questions and the implementation of conservation focused actions.

Ecosystem for Leading Innovation in Plasma Science and Engineering (ECLIPSE)
Solicitation Number: NSF 24-503
Deadline: due dates vary by division
Description: Plasma science is a transdisciplinary field of research where fundamental studies in many disciplines, including plasma physics, plasma chemistry, materials science, and space science, come together to advance knowledge for discovery and technological innovation. The primary goal of the ECosystem for Leading Innovation in Plasma Science and Engineering (ECLIPSE) program is to identify and capitalize on opportunities for bringing fundamental plasma science investigations to bear on problems of societal and technological need within the scope of science and engineering supported by the participating NSF programs.

Campus Cyberinfrastructure (CC*)
Solicitation Number: NSF 24-530
Deadline: April 22, 2024; October 15, 2024
Description: The Campus Cyberinfrastructure (CC*) program invests in coordinated campus-level cyberinfrastructure improvements, innovation, integration, and engineering for science applications and distributed research projects. Projects that help overcome disparities in cyber-connectivity associated with geographic location, and thereby advance the geography of innovation and enable populations based in these locales to become more nationally competitive in science, technology, engineering, and mathematics (STEM) research and education are particularly encouraged. Science-driven requirements are the primary motivation for any proposed activity.

Research Experiences for Teachers (RET) in Engineering and Computer Science
Solicitation Number: NSF 24-503
Deadline: October 09, 2024; Second Wednesday in October, Annually Thereafter
Description: This program supports authentic summer research experiences for K-14 educators to foster long-term collaborations between universities, community colleges, school districts, and industry partners. With this solicitation, the Directorates for Engineering and Computer and Information Science and Engineering focus on a reciprocal exchange of expertise between K-14 educators and research faculty and (when applicable) industry mentors. K-14 educators will enhance their scientific disciplinary knowledge in engineering or computer science and translate their research experiences into classroom activities and curricula.

International Research Experiences for Students (IRES)
Solicitation Number: NSF 24-506
Deadline: October 28, 2024; Fourth Monday in October, Annually Thereafter
Description: The IRES program supports international research and research-related activities for U.S. science and engineering students. The IRES program contributes to development of a diverse, globally engaged workforce with world-class skills. IRES focuses on active research participation by undergraduate and/or graduate students in high quality international research, education and professional development experiences in NSF-funded research areas.

Designing Synthetic Cells Beyond the Bounds of Evolution (Designer Cells)
Solicitation Number: NSF 24-505
Deadline: Feb 1, 2026; Feb 1 2028
Description: The goal of this solicitation is to support research that (1) develops cell-like systems to identify the minimal requirements for the processes of life, (2) designs synthetically-modified cells to address fundamental questions in the evolution of life or to explore biological diversity beyond that which currently exists in nature, and (3) leverages basic research in cell design to build novel synthetic cell-like systems and cells for innovative biotechnology applications. Highest funding priority is given to proposals that have outstanding intellectual merit and broader impacts, while proposals with weaknesses in either category (or those that are perceived as likely to have an incremental impact) will not be competitive.

Ethical and Responsible Research (ER2)
Solicitation Number: NSF 23-630
Deadline: 4th Thursday in January, annually
Description: The ER2 program encourages research that generates an improved understanding of how and why research approaches, practices and norms foster or hinder ethics education and training of science, technology, engineering and mathematics (STEM) researchers and practitioners. The program aims to support the formation, improvement and dissemination of ethical research practices in STEM fields and to foster organizational cultures that value and reward academic and research integrity. The program also seeks to motivate, inform and educate STEM researchers, including undergraduate and graduate students, postdoctoral fellows and faculty, to identify and explore the ethical dimensions of research so that their work is responsive to the needs and values of society.

Accelerating Research through International Network-to-Network Collaborations (AccelNet)
Solicitation Number: NSF 23-619
Deadline: September 16, 2024; 3rd Monday in September, Annually Thereafter
Description: The contemporary research landscape is a collaborative and international enterprise requiring high level coordination among multi-disciplinary, cross-cultural teams. As such, the Accelerating Research through International Network-to-Network Collaborations program (AccelNet) values cooperation over competition. Program goals are to 1) leverage prior NSF support for building research capacity towards activities that launch international research network of networks (NoN) that will lead to an accelerated advancement of an area of science after the award period and 2) recruit and foster a diverse and internationally competent US-based workforce trained in conducting and leading multi-team international collaboration. Successful proposals will demonstrate that the proposed activities will: 1) accelerate scientific research at a rate that would not be possible without concerted international cooperation in research planning; 2) make NoN members more competitive for research awards following the period of award; 3) recruit and foster a US-based diverse and internationally competent workforce trained in conducting and leading multi-team international collaboration. Proposals must include detailed plans for collaborative networking activities that will result in a synergy of effort across the entire NoN.

Focused Research Groups in the Mathematical Sciences (FRGMS)
Solicitation Number: NSF 23-621
Deadline: 2nd Wednesday in December
Description: The purpose of the Focused Research Group activity is to support collaborative groups employing innovative methods to solve specific, major research challenges in the mathematical sciences. A major challenge is an outstanding problem of significant importance that requires the focused and synergistic efforts of a collaborative group to solve, and whose solution will have wide impacts in the mathematical sciences and potentially in other areas.

Solicitation Number: PD 23-1401
Deadline: Proposals accepted anytime
Description: The goals of the Catalysis program are to increase fundamental understanding in catalytic engineering science and to advance the development of catalysts and catalytic reactions that are beneficial to society. Research should focus on critical challenges and opportunities in both new and proven catalysis technologies. Areas of emphasis may include novel catalyst compositions, structures, operating environment, data science tools, theory, and modeling – preferably in various combinations as dictated by the specific reaction and related knowledge and technology gaps. Target applications include fuels, specialty and bulk chemicals, environmental catalysis, biomass conversion to fuels and chemicals, greenhouse gas mitigation, recycling of waste materials, generation of solar hydrogen, as well as efficient routes to energy utilization.

Mathematical Sciences Research Institutes
Solicitation Number: NSF 23-606
Deadline: March 14, 2029
Description: Mathematical Sciences Research Institutes are national resources that aim to advance research in the mathematical sciences through programs supporting discovery and dissemination of knowledge in mathematics and statistics and enhancing connections to related fields in which the mathematical sciences can play important roles. Institute activities help focus the attention of some of the best mathematical minds on problems of particular importance and timeliness. Institutes are also community resources that involve a broad segment of U.S.-based mathematical sciences researchers in their activities. The goals of the Mathematical Sciences Research Institutes program include advancing research in the mathematical sciences, increasing the impact of the mathematical sciences in other disciplines, and expanding the talent base engaged in mathematical research in the United States.

National Science Foundation Research Traineeship (NRT) Program
Solicitation Number: NSF 21-536
Deadline: September 6, Annually
Description: The NSF Research Traineeship (NRT) program seeks proposals that explore ways for graduate students in research-based master’s and doctoral degree programs to develop the skills, knowledge, and competencies needed to pursue a range of STEM careers. The program is dedicated to effective training of STEM graduate students in high priority interdisciplinary or convergent research areas, through a comprehensive traineeship model that is innovative, evidence-based, and aligned with changing workforce and research needs. Proposals are requested that address any interdisciplinary or convergent research theme of national priority, as noted above.

Research Training Groups in the Mathematical Sciences (RTG)
Solicitation Number: NSF 23-579
Deadline: 2nd Tuesday in August
Description: The long-range goal of the Research Training Groups in the Mathematical Sciences program is to strengthen the nation's scientific competitiveness by increasing the number of well-prepared U.S. citizens, nationals, and permanent residents who pursue careers in the mathematical sciences, be they in academia, government, or industry. The RTG program supports efforts to improve research training by involving undergraduate students, graduate students, postdoctoral associates, and faculty members in structured research groups pursuing coherent research programs. Research groups supported by RTG must include vertically-integrated activities that span the entire spectrum of educational levels from undergraduates through postdoctoral associates.

Centers of Research Excellence in Science and Technology (CREST Centers)
Solicitation Number: NSF 23-595
Deadline: Preliminary proposals (required): 1st Friday in December; Full applications: 1st Friday in December
Description: CREST Center awards provide support to enhance the research capabilities of Minority-serving institutions (MSIs) through the establishment of centers that effectively integrate education and research. CREST Center awards promote the development of new knowledge, enhancements of the research productivity of individual faculty, and an expanded presence of students historically underrepresented in science, technology, engineering, and mathematics (STEM) disciplines. Successful CREST Center proposals will demonstrate a clear vision and integration of STEM research and education and will align with the mission of the Division of Equity for Excellence in STEM (EES) with respect to the development of a diverse STEM workforce. CREST Centers are also expected to provide leadership by meaningfully involving the efforts of those faculty, students, and postdoctoral researchers who are traditionally underrepresented in STEM at all levels. Centers are required to use evidence-based and innovative strategies to address salient broadening participation and workforce development issues, such as recruitment, retention, and mentorship of participants from underrepresented groups. Successful proposals are expected to achieve national research competitiveness, broaden participation in STEM, and generate sustained, non-CREST funding from federal, state, and/or private-sector sources.

CyberCorps(R) Scholarship for Service (SFS)
Solicitation Number: NSF 23-574
Deadline: July 15, Annually
Description: The goals of the CyberCorps® Scholarship for Service (SFS) program are aligned with the U.S. strategy to develop a superior cybersecurity workforce. The program goals are to: (1) increase the number of qualified and diverse cybersecurity candidates for government cybersecurity positions; (2) improve the national capacity for the education of cybersecurity professionals and research and development workforce; (3) hire, monitor, and retain high-quality CyberCorps® graduates in the cybersecurity mission of the Federal Government; and (4) strengthen partnerships between institutions of higher education and federal, state, local, and tribal governments. While all three agencies work together on all four goals, NSF’s strength is in the first two goals; OPM’s in goal (3); and DHS in goal (4). The SFS Program welcomes proposals to establish or to continue scholarship programs in cybersecurity. A proposing institution must provide clearly documented evidence of a strong existing academic program in cybersecurity.

Thermal Transport Processes (TTP)
Solicitation Number: PD-23-1406
Deadline: Continuously accepted
Description: The Thermal Transport Processes program supports engineering research projects that lay the foundation for new advances in thermal transport phenomena. These projects should either develop new fundamental knowledge or combine existing knowledge in thermodynamics, fluid mechanics, and heat and mass transfer to probe new areas of innovation in thermal transport processes. The program seeks transformative projects with the potential for improving basic understanding, predictability and application of thermal transport processes.

Partnerships for Innovation (PFI)
Solicitation Number: NSF 23-538
Deadline: Limited Submission (one new or resubmitted PFI-RP proposal per deadline): First Tuesday in January, May, September, Annually
Description: The Partnerships for Innovation (PFI) Program within the Division of Translational Impacts (TI) offers researchers from all disciplines of science and engineering funded by NSF the opportunity to perform translational research and technology development, catalyze partnerships and accelerate the transition of discoveries from the laboratory to the marketplace for societal benefit. The intended outcomes of both PFI-TT and PFI-RP tracks are: a) the commercialization of new intellectual property derived from NSF-funded research outputs; b) the creation of new or broader collaborations with industry (including increased corporate-sponsored research); c) the licensing of NSF-funded research outputs to third party corporations or to start-up companies funded by a PFI team; and d) the training of future innovation and entrepreneurship leaders.

NSF Scholarships in Science, Technology, Engineering, and Mathematics Program (S-STEM)
Solicitation Number: NSF 24-511
Deadline: March 04, 2025; 1st Tuesday in March, Annually Thereafter
Description: The main goal of the S-STEM program is to enable low-income students with academic ability, talent or potential to pursue successful careers in promising STEM fields. Ultimately, the S-STEM program seeks to increase the number of academically promising low-income students who graduate with a S-STEM eligible degree and contribute to the American innovation economy with their STEM knowledge. The S-STEM program encourages collaborations, including but not limited to partnerships among different types of institutions; collaborations of S-STEM eligible faculty, researchers, and academic administrators focused on investigating the factors that affect low-income student success (e.g., institutional, educational, behavioral and social science researchers); and partnerships.

Training-based Workforce Development for Advanced Cyberinfrastructure
Solicitation Number: NSF 23-520
Deadline: 3rd Thursday in January, Annually
Description: This program seeks to prepare, nurture, and grow the national scientific research workforce for creating, utilizing, and supporting advanced cyberinfrastructure to enable and potentially transform fundamental science and engineering research and education and contribute to the Nation's overall economic competitiveness and security.

Division of Molecular and Cellular Biosciences Core Programs (MCB)
Solicitation Number: NSF 23-548
Deadline: Proposals Accepted Anytime
Description: MCB supports research that promises to uncover the fundamental properties of living systems across atomic, molecular, subcellular, and cellular scales. The program gives high priority to projects that advance mechanistic understanding of the structure, function, and evolution of molecular, subcellular, and cellular systems, especially research that aims at quantitative and predictive knowledge of complex behavior and emergent properties. MCB encourages research exploring new concepts in molecular and cellular biology, while incorporating insights and approaches from other scientific disciplines, such as chemistry, computer science, engineering, mathematics, and physics, to illuminate principles that govern life at the molecular and cellular level. MCB also encourages research that exploits experimental and theoretical approaches and utilizes a diverse spectrum of model and non-model animals, plants, and microbes across the tree of life. Proposals that pursue potentially transformative ideas are welcome, even if these entail higher risk.

EDU Core Research: Building Capacity in STEM Education Research (ECR: BCSER)
Solicitation Number: NSF 22-548
Deadline: 4th Friday in February, Annually
Description: ECR’s Building Capacity in STEM Education Research (ECR: BCSER) supports projects that build investigators’ capacity to carry out high-quality STEM education research that will enhance the nation’s STEM education enterprise. In addition, ECR: BCSER seeks to broaden the pool of researchers who can advance knowledge regarding STEM learning and learning environments, broadening participation in STEM fields, and STEM workforce development. Specifically, ECR: BCSER supports activities that enable researchers to expand their areas of expertise and acquire the requisite knowledge and skills to conduct rigorous research in STEM education. Career development may be accomplished through investigator-initiated professional development and research projects or through institutes that enable researchers to integrate methodological strategies with theoretical and practical issues in STEM education.

Oceanographic Facilities and Equipment Support
Solicitation Number: NSF 23-525
Deadline: January 10th, annually
Description: These awards are made for the procurement, conversion and/or upgrade, enhancement, or annual operation of platforms in the ocean, coastal and near-shore waters, and Great Lakes. Awards are generally directed specifically to support facilities that lend themselves to shared use within the broad range of Federally supported research and education programs. The primary objective of these awards is to ensure the availability of appropriate oceanographic facilities for Federally funded investigators and educators.

Major Research Instrumentation Program (MRI)
Solicitation Number: NSF 23-519
Deadline: November 15, 2024; November 14, 2025; November 16, 2026
Description: Supports requests for up to $4 million from NSF for the development or acquisition of multi-user research instruments that are critical to the advancement of science and engineering. Track 1: $100,000 - $1,400,000; Track 2: $1,400,000 - $4,000,000; Track 3: $100,000 - $4,000,000 that include the purchase, installation, operation, and maintenance of equipment and instrumentation to conserve or reduce the consumption of helium. Institutions may submit no more than one Track 3 proposal.

Solicitation Number: PD 18-1269
Deadline: December 1 - December 15, Annually
Description: The Statistics Program supports research in statistical theory and methods, including research in statistical methods for applications to any domain of science and engineering. The theory forms the base for statistical science. The methods are used for stochastic modeling, and the collection, analysis and interpretation of data. The methods characterize uncertainty in the data and facilitate advancement in science and engineering. The Program encourages proposals ranging from single-investigator projects to interdisciplinary team projects.

Research and Mentoring for Postbaccalaureates in Biological Sciences (RaMP)
Solicitation Number: NSF 23-514
Deadline: 3rd Thursday in January, Annually
Description: This program invites the submission of proposals to establish networks to support full-time research, mentoring, and training for recent college graduates who have had few or no research or training opportunities during college in research fields typically supported by the Directorate of Biological Sciences. Projects are expected to train individuals for a range of potential career pathways in the biological sciences including: research-focused MS or PhD graduate programs; entry-level positions in industry, federal, tribal, or state agencies, education and research centers, or not-for-profit science-based organizations; or other STEM careers.

Solicitation Number: PD 22-1530
Deadline: Proposals accepted anytime
Description: The goals of the paleoclimate program are to: (i) provide a baseline for present climate variability and future climate trends, and (ii) improve the understanding of the physical, chemical, and biological processes that influence climate variability and trends over the long-term. Research topics include observational and modeling studies of past climate variability and its drivers and studies that develop new paleoclimate proxies and records. Competitive proposals will address specific aspects of scientific uncertainty for their proposed research.

Biology Integration Institutes (BII)
Solicitation Number: NSF 23-511
Deadline: February 18, 2025
Description: Biology has transformed science over the last century through discoveries that cross subdisciplines from the molecular to the organismal to the ecosystem level. While making great progress, biology has also slowly fragmented into subdisciplines, creating a dynamic tension between unifying principles and increasingly reductionist pursuits. The aim of this solicitation is to bring researchers together around the common goal of understanding how the processes that sustain life and enable biological innovation operate and interact within and across different scales of organization, from molecules to cells, tissues to organisms, species, ecosystems, biomes and the entire Earth. The Biology Integration Institutes (BII) program supports collaborative teams of researchers investigating questions that span multiple disciplines within and beyond biology.

Improving Undergraduate STEM Education: Directorate for STEM Education (IUSE: EDU)
Solicitation Number: NSF 23-510
Deadline: Level 1: Third Wednesday in January; Level 2 and 3: Third Wednesday in July, Annually
Description: This is a core NSF STEM education program that seeks to promote novel, creative, and transformative approaches to generating and using new knowledge about STEM teaching and learning to improve STEM education for undergraduate students. The program is open to application from all institutions of higher education and associated organizations. NSF places high value on educating students to be leaders and innovators in emerging and rapidly changing STEM fields as well as educating a scientifically literate public.

Expanding AI Innovation through Capacity Building and Partnerships (ExpandAI)
Solicitation Number: NSF 23-506
Deadline: June 24, 2024; October 18, 2024; March 10, 2025; June 23, 2025; October 17, 2025
Description: The National Science Foundation and its partners support the continued growth of a broad and diverse interdisciplinary research community for the advancement of AI and AI-powered innovation, providing a unique opportunity to broadly promote the NSF vision and core values, especially inclusion and collaboration. The Expanding AI Innovation through Capacity Building and Partnerships (ExpandAI) program aims to significantly broaden participation in AI research, education, and workforce development through capacity development projects and through partnerships within the National AI Research Institutes ecosystem.

Dynamics of Integrated Socio-Environmental Systems (DISES)
Solicitation Number: NSF 20-579
Deadline: November 15, Annually
Description: The DISES Program supports research projects that advance basic scientific understanding of integrated socio-environmental systems and the complex interactions (dynamics, processes, and feedbacks) within and among the environmental (biological, physical and chemical) and human ("socio") (economic, social, political, or behavioral) components of such a system. The program seeks proposals that emphasize the truly integrated nature of a socio-environmental system versus two discrete systems (a natural one and a human one) that are coupled. DISES projects must explore a connected and integrated socio-environmental system that includes explicit analysis of the processes and dynamics between the environmental and human components of the system.

Build and Broaden: Enhancing Social, Behavioral and Economic Science Research and Capacity at Minority-Serving Institutions (B2)
Solicitation Number: NSF 22-638
Deadline: Third Thursday in January, Annually
Description: Build and Broaden (B2) supports fundamental research and research capacity across disciplines at MSIs and encourages research collaborations with scholars at MSIs. Growing the STEM workforce is a national priority. Proposals are invited from single principal investigators based at MSIs and from multiple co-investigators from groups of MSIs. Principal investigators who are not affiliated with MSIs may submit proposals, but must collaborate with PIs, co-PIs, or senior personnel from MSIs.

Paleo Perspectives on Present and Projected Climate (P4CLIMATE)
Solicitation Number: NSF 22-612
Deadline: October 20, Annually
Description: The PALEO PERSPECTIVES ON PRESENT AND PROJECTED CLIMATE (P4CLIMATE) competition is a coordinated paleoclimate science initiative that is funded by the National Science Foundation (NSF) Divisions of Atmospheric and GeoSpace Sciences (AGS), Earth Sciences (EAR), Ocean Sciences (OCE), and Office of Polar Programs (OPP) in the Geosciences (GEO) Directorate. The annual P4CLIMATE competition supports the scientific objectives of the National Science Foundation by fostering interdisciplinary research and synthesis of climate data. The goal of the interdisciplinary P4CLIMATE solicitation is to utilize observational and modeling studies to provide paleo perspectives addressing the two research themes: 1) Past Regional and Seasonal Climate; and 2) Past Climate Forcing, Sensitivity, and Feedbacks.

Computer and Information Science and Engineering: Core Programs
Solicitation Number: NSF 22-631
Deadline: OAC Core Projects and MEDIUM Projects: Dec 1–Dec 22, Annually; Small Projects: Oct 1–Sep 30, Annually
Description: The NSF CISE Directorate supports research and education projects that develop new knowledge in all aspects of computing, communications, and information science and engineering, as well as advanced cyberinfrastructure, through a variety of core programs.

Computer and Information Science and Engineering (CISE): Core Programs, Large Projects
Solicitation Number: NSF 23-524
Deadline: September 30, 2024; September 28, 2026
Description: This solicitation invites proposals on bold new ideas tackling ambitious and fundamental research problems within scope of one or more of the participating CISE divisions core programs listed above, and that are well suited to a large-scale integrated collaborative effort. Teams should consist of two or more investigators (PI, co-PI(s), or other Senior Personnel) with complementary expertise. Investigators are strongly encouraged to come together within or across disciplines and/or institutions and combine their creative talents to identify compelling, transformative research agendas where the impact of the results will exceed that of the sum of each of their individual contributions. Investigators are especially encouraged to seek out partnerships in a wide class of institutions that together produce innovative approaches to the proposed research. Proposals that are focused on research infrastructure are not appropriate for this solicitation. Proposers are invited to submit proposals with total budgets from $3,000,000 to $5,000,000 and durations up to five years.

Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science
Solicitation Number: NSF 22-622
Deadline: 4th Tues in Oct, annually
Description: NSF INCLUDES seeks to motivate and accelerate collaborative infrastructure building to advance equity and sustain systemic change to broaden participation in STEM fields at scale. Significant advancement in the inclusion of groups that have historically been excluded from or underserved in STEM will result in a new generation of STEM talent and leadership to secure the Nation’s future and long-term economic competitiveness. NSF offers support for five types of projects that connect and contribute to the National Network: (1) Design and Development Launch Pilots, (2) Collaborative Change Consortia, (3) Alliances, (4) Network Connectors, and (5) Conferences. The NSF INCLUDES National Network is a multifaceted collaboration of agencies, organizations, and individuals working collectively to broaden participation in STEM.

Focused Research Groups in the Mathematical Sciences (FRGMS)
Solicitation Number: NSF 16-577
Deadline: Second Wed in Sep, annually
Description: The purpose of the Focused Research Group activity is to support collaborative groups employing innovative methods to solve specific, major research challenges in the mathematical sciences. A major challenge is an outstanding problem of significant importance that requires the focused and synergistic efforts of a collaborative group to solve, and whose solution will have wide impacts in the mathematical sciences and potentially in other areas. Groups may include, in addition to statisticians and mathematicians, researchers from other science and engineering disciplines appropriate for the proposed research. Risky projects are welcome. Interdisciplinary projects are welcome. Projects should be timely, limited in duration to up to three years, and substantial in their scope and impact for the mathematical sciences.

Ocean Sciences Postdoctoral Research Fellowships (OCE-PRF)
Solicitation Number: NSF 22-628
Deadline: Second Friday in November
Description: Supports independent postdoctoral research on any topic supported by the Division of Ocean Sciences and provides professional development with a focus on developing mentoring skills to broaden participation of underrepresented groups in STEM.

Advanced Technologies and Instrumentation for the Astronomical Sciences (ATI)
Solicitation Number: NSF 22-627
Deadline: Nov 15, annually
Description: This program provides individual investigator and collaborative research grants for the development of new technologies and instrumentation for use in ground-based astronomy and astrophysics. The program supports achieving the science objectives of the Division of Astronomical Sciences. The development of innovative, potentially transformative, technologies and instruments are sought, even at high technical risk.

Mathematical Biology (NSF)
Solicitation Number: PD 22-7334
Deadline: proposals accepted anytime
Description: The Mathematical Biology Program supports research in areas of applied and computational mathematics with relevance to the biological sciences. Successful proposals must demonstrate mathematical innovation, biological relevance and significance, and strong integration between mathematics and biology.

Division of Chemistry: Disciplinary Research Programs (CHE-DRP)
Solicitation Number: NSF 22-605
Deadline: CAT, CSDM-B, SYN: Sep 1 - Sep 30, annually; CMI, ECS, MSN: Oct 1-Oct 31, annually
Description: This solicitation applies to six (of the nine) CHE Disciplinary Research Programs: Chemical Catalysis (CAT); Chemical Measurement and Imaging (CMI); Chemical Structure Dynamics and Mechanisms-B (CSDM-B); Chemical Synthesis (SYN); Environmental Chemical Sciences (ECS); and Macromolecular, Supramolecular and Nanochemistry (MSN).

Division of Chemistry: Disciplinary Research Programs: No Deadline Pilot (CHE-DRP:NDP)
Solicitation Number: NSF 22-606
Deadline: Proposals Accepted Anytime
Description: With this solicitation, the Division of Chemistry is piloting the removal of deadlines for the submission of proposals to the CLP, CSDM-A and CTMC Programs. The no-deadline pilot seeks to assess the benefits and challenges of removing deadlines in proposal submission for the chemistry research community: the removal of deadlines on proposal submission is intended to allow principal investigators (PIs) more flexibility and better facilitate interdisciplinary research. It may, however, have unanticipated consequences for PIs, reviewers, and institutions.

Condensed Matter and Materials Theory
Solicitation Number: NSF 23-611
Deadline: proposals accepted anytime
Description: CMMT supports theoretical and computational materials research in the topical areas represented in DMR's other Topical Materials Research Programs (these are also variously known as Individual Investigator Award (IIA) Programs, or Core Programs, or Disciplinary Programs), which are: Condensed Matter Physics (CMP), Biomaterials (BMAT), Ceramics (CER), Electronic and Photonic Materials (EPM), Metals and Metallic Nanostructures (MMN), Polymers (POL), and Solid State and Materials Chemistry (SSMC). The CMMT program supports fundamental research that advances conceptual understanding of hard and soft materials, and materials-related phenomena; the development of associated analytical, computational, and data-centric techniques; and predictive materials-specific theory, simulation, and modeling for materials research. First-principles electronic structure, quantum many-body and field theories, statistical mechanics, classical and quantum Monte Carlo, and molecular dynamics, are among the methods used in the broad spectrum of research supported in CMMT.

Division of Materials Research: Topical Materials Research Programs (DMR:TMRP)
Solicitation Number: NSF 23-612
Deadline: proposals accepted anytime
Description: Research supported by the Division of Materials Research (DMR) focuses on advancing the fundamental understanding of materials, materials discovery, design, synthesis, characterization, properties, and materials-related phenomena. DMR awards enable understanding of the electronic, atomic, and molecular structures, mechanisms, and processes that govern nanoscale to macroscale morphology and properties; manipulation and control of these properties; discovery of emerging phenomena of matter and materials; and creation of novel design, synthesis, and processing strategies that lead to new materials with unique characteristics. These discoveries and advancements transcend traditional scientific and engineering disciplines.

Building Synthetic Microbial Communities for Biology, Mitigating Climate Change, Sustainability, and Biotechnology (Synthetic Communities)
Solicitation Number: NSF 22-607
Deadline: August 01, 2024
Description: The goal of this solicitation is to support research that addresses one or more of the three themes: 1) define the underlying mechanisms or rules that drive the formation, maintenance or evolution of synthetic microbial communities, 2) use synthetic microbial communities to address fundamental biological questions, including questions in molecular biology, cellular/organismal biology, ecology and evolution and/or 3) build synthetic communities with biotechnology, bio-economy or environmental engineering applications, including but not limited to the production of novel bio-renewable chemicals, bio-degradation of recalcitrant or "forever chemicals," enabling a circular bio-economy, fostering sustainable agriculture and mitigating the impacts of climate change.

Mid-Career Advancement (MCA)
Solicitation Number: NSF 22-603
Deadline: Feb 1 - Mar 1, annually
Description: The MCA program offers an opportunity for scientists and engineers at the mid-career stage (see restrictions under Additional Eligibility Information) to substantively enhance and advance their research program and career trajectory. Mid-career scientists are at a critical career transition stage where they need to advance their research programs to ensure long-term productivity and creativity but are often constrained by service, teaching, or other activities that limit the amount of time devoted to research. MCA support is expected to help lift these constraints to reduce workload inequities and enable a more diverse scientific workforce (more women, persons with disabilities, and individuals from groups that have been underrepresented) at high academic ranks.

Division of Physics: Investigator-Initiated Research Projects (PHY)
Solicitation Number: NSF 23-615
Deadline: November and December, annually (deadlines vary by program)
Description: The Division of Physics (PHY) supports physics research and the preparation of future scientists in the nation’s colleges and universities across a broad range of physics disciplines that span scales of space and time from the largest to the smallest and the oldest to the youngest. The Division is comprised of disciplinary programs covering experimental and theoretical research in the following major subfields of physics: Atomic, Molecular and Optical Physics; Elementary Particle Physics; Gravitational Physics; Integrative Activities in Physics; Nuclear Physics; Particle Astrophysics; Physics at the Information Frontier; Physics of Living Systems; Plasma Physics; and Quantum Information Science. Principal Investigators (PIs) are encouraged to consider including specific efforts to increase diversity of the physics community and broaden participation of under-represented groups in Science, Technology, Engineering, and Mathematics (STEM).

Improving Undergraduate STEM Education: Hispanic-Serving Institutions (HSI Program)
Solicitation Number: NSF 22-611
Deadline: Tracks 1 & 2: 2nd Wednesday in February, Annually; Tracks 1-3: Last Wednesday in August, Annually
Description: The goals of the HSI program are to enhance the quality of undergraduate science, technology, engineering, and mathematics (STEM) education and to increase the recruitment, retention, and graduation rates of students pursuing associates or baccalaureate degrees in STEM. Achieving these, given the diverse nature and context of the HSIs, requires additional strategies that support building capacity at HSIs through innovative approaches: to incentivize institutional and community transformation; and to promote fundamental research (i) on engaged student learning, (ii) about what it takes to diversify and increase participation in STEM effectively, and (iii) that improves our understanding of how to build institutional capacity at HSIs. Intended outcomes of the HSI Program include broadening participation of students that are historically underrepresented in STEM and expanding students' pathways to continued STEM education and integration into the STEM workforce.

Opportunities for Promoting Understanding through Synthesis (OPUS)
Solicitation Number: NSF 22-591
Deadline: Proposals Accepted Anytime
Description: The OPUS program is targeted to individuals, typically at later-career stages, who have contributed significant insights to a field or body of research over time. The program provides an opportunity to revisit and synthesize that prior research into a unique, integrated product(s) useful to the scientific community, now and in the future. All four clusters within the Division of Environmental Biology (Ecosystem Science, Evolutionary Processes, Population and Community Ecology, and Systematics and Biodiversity Science) encourage the submission of OPUS proposals.

Geobiology and Low-Temperature Geochemistry (GG)
Solicitation Number: NSF 22-578
Deadline: Proposals Accepted Anytime
Description: The Geobiology and Low-Temperature Geochemistry Program supports research on geochemical processes in terrestrial Earth's surface systems, as well as the interaction of geochemical and biological processes. Proposals may address field, laboratory, theoretical, or modeling studies of these processes and related mechanisms at all spatial and temporal scales. The Geobiology and Low-Temperature Geochemistry Program is interested in supporting transformational and cutting-edge research. The Program also supports the development of geochemical proxies and analytical techniques. The Program is highly interdisciplinary and interfaces with other programs within the Geosciences Directorate, and with programs across NSF, including in biology, chemistry, and engineering.

Facilities for Atmospheric Research and Education (FARE)
Solicitation Number: PD 04-1529
Deadline: continuous
Description: TheTo facilitate fundamental research in the atmospheric sciences, the Division of Atmospheric and Geospace Sciences (AGS) supports state-of-the-art instruments and facilities through the Facilities for Atmospheric Research and Education (FARE) Program. The FARE Program includes the Lower Atmosphere Observing Facilities (LAOF) and the Community Instruments and Facilities (CIF).

Pathways into the Earth, Ocean, Polar and Atmospheric & Geospace Sciences (GEOPAths)
Solicitation Number: NSF 22-555
Deadline: proposals accepted anytime
Description: GEOPAths invites proposals that specifically address the current needs and opportunities related to education, learning, training and professional development within the geosciences community through the formation of STEM Learning Ecosystems that engage students in the study of the Earth, its oceans, polar regions and atmosphere. The primary goal of the GEOPAths funding opportunity is to increase the number of students pursuing undergraduate and/or postgraduate degrees through the design and testing of novel approaches that engage students in authentic, career-relevant experiences in geoscience. In order to broaden participation in the geosciences, engaging students from historically excluded groups or from non-geoscience degree programs is a priority.

Geophysics (PH)
Solicitation Number: NSF 22-563
Deadline: proposals accepted anytime
Description: The Geophysics Program supports basic research in the physics of the solid earth to explore its composition, structure, and processes from the Earth's surface to its deepest interior. The program's disciplinary focus spans geodesy, geodynamics, geomagnetism, heat flow, mineral physics, potential fields, seismology, rock mechanics and deformation. Within these fields, the program encourages a wide range of laboratory, field, theoretical, and/or computational studies, and encourages new methods, approaches and innovative research directions. Research questions the program addresses include but are not limited to 1) understanding geohazards, such as the fundamental geophysical processes underpinning earthquakes, volcanoes and mass flows; 2) crustal and lithospheric structure and dynamics including faulting, subduction, rifting and mountain-building processes; 3) mantle composition, structure, dynamics and evolution; 4) core structure and dynamics, geodynamo, and core-mantle interactions; 5) global and planetary-scale processes, early Earth formation and evolution, isostatic adjustment, and the magnetic field.

Coupling, Energetics, and Dynamics of Atmospheric Regions
Solicitation Number: NSF 22-575
Deadline: First Friday in May, Annually
Description: The Coupling, Energetics, and Dynamics of Atmospheric Regions (CEDAR) program is a broad-based research program with the goal of understanding the behavior of atmospheric regions from the middle atmosphere upward through the thermosphere and ionosphere into the exosphere in terms of coupling, energetics, chemistry, and dynamics on regional and global scales. These processes are related to the sources of perturbations that propagate upward from the lower atmosphere as well as to solar radiation and particle inputs from above. The activities within this program include observations from ground-based and space-based platforms, theory, and modeling.

Earth Sciences Instrumentation and Facilities
Solicitation Number: NSF 22-577
Deadline: Proposals accepted anytime
Description: The NSF Division of Earth Sciences (EAR) hereby solicits proposals for research infrastructure that is necessary to advance understanding of the Earth System including: the structure, properties and dynamics of the solid Earth and the interactions between the solid Earth and its biosphere, hydrosphere, cryosphere and atmosphere; the history and evolution of life; and the history and dynamics of Earth’s climate. The EAR Instrumentation and Facilities Program (EAR/IF) will support meritorious requests for instrument-based and human research infrastructure that will advance understanding of the Earth system, contribute toward training a diverse geoscience workforce, and encourage efforts to support belonging, accessibility, justice, equity, diversity, and inclusion (BAJEDI).

Biological Oceanography
Solicitation Number: NA
Deadline: accepted continuously
Description: The Biological Oceanography Program supports fundamental research in biological oceanography and marine ecology (populations to the ecosystems) broadly defined: relationships among aquatic organisms and their interactions with the environments of the oceans or Great Lakes. Projects submitted to the program are often interdisciplinary efforts that may include participation by other OCE or BIO Programs.

Cyber-Physical Systems (CPS)
Solicitation Number: NSF 21-551
Deadline: SMALL and MEDIUM proposals: anytime
Description: Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computation and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will expand the horizons of these critical systems. The CPS program aims to develop the core research needed to engineer these complex CPS, some of which may also require dependable, high-confidence, or provable behaviors. Core research areas of the program include control, data analytics, and machine learning including real-time learning for control, autonomy, design, Internet of Things (IoT), mixed initiatives including human-in- or human-on-the-loop, networking, privacy, real-time systems, safety, security, and verification. By abstracting from the particulars of specific systems and application domains, the CPS program seeks to reveal cross-cutting, fundamental scientific and engineering principles that underpin the integration of cyber and physical elements across all application domains. The program additionally supports the development of methods, tools, and hardware and software components based upon these cross-cutting principles, along with validation of the principles via prototypes and testbeds. This program also fosters a research community that is committed to advancing education and outreach in CPS and accelerating the transition of CPS research into the real world.

Solicitation Number: PD 18-5115
Deadline: varies by field of study
Description: The NSF's Big Idea “Windows on the Universe” is implemented through this WoU-MMA program. WoU-MMA identifies three categories of messengers - electromagnetic waves, high-energy particles including neutrinos and cosmic rays, and gravitational waves. The goals of WoU-MMA are to build the capabilities and accelerate the synergy and interoperability of the three messengers to realize integrated, multi-messenger astrophysical explorations of the Universe. The WoU-MMA program welcomes proposals in any area of research supported through the participating divisions that address at least one of the following criteria: Coordination: Hardware, software, or other infrastructure to coordinate observations involving more than one messenger. Observations: Observations of astrophysical objects or phenomena that are potentially sources of more than one messenger, including the use of existing observatories, experiments, and data archives, as well as the development and construction of new capabilities for advancing multi-messenger astrophysics. Interpretation: Theory, experiment, simulations and other activities to understand or interpret observations of astrophysical objects that are sources of more than one messenger.

Navigating the New Arctic (NNA)
Solicitation Number: NSF 22-520
Deadline: 2nd Wednesday in February, Annually
Description: Navigating the New Arctic (NNA) embodies an important forward-looking response by the Foundation to these profound challenges. NNA seeks innovations in fundamental convergence research across the social, natural, environmental, computing and information sciences, and engineering that address the interactions or connections among natural and built environments and social systems, and how these connections inform our understanding of Arctic change and its local and global effects. This solicitation requests proposals that fall within one of three tracks: NNA Incubator Grants, dedicated to developing convergent teams to carry out research projects of larger scope in the future; NNA Research Grants, aimed to support creative projects on fundamental research that address convergent scientific and engineering challenges related to the rapidly changing Arctic; and NNA Collaboratory Grants, designed to support collaborative teams undertaking research and training initiatives addressing grand challenges related to the rapidly changing New Arctic.

Computational Mathematics
Solicitation Number: PD 16-1271
Deadline: Submission window: November 16 - December 1, annually
Description: Supports mathematical research in areas where computation plays a central and essential role, emphasizing analysis, development, and implementation of theoretically justified and efficient algorithms. The combination of these elements resulting in innovative computational methods is a hallmark of the program. Proposals ranging from single investigator to interdisciplinary team projects that not only create and analyze new computational mathematics techniques but also implement them to model, study, and solve important application problems are strongly encouraged, as is providing opportunities for rigorous mathematical training of junior computational mathematicians through research involvement.

Organismal Response to Climate Change (ORCC)
Solicitation Number: NSF 23-622
Deadline: November 19, 2024; 3rd Tuesday in November, Annually Thereafter
Description: This solicitation calls for proposals that integrate the study of genomic, physiological, structural, developmental, neural, or behavioral mechanisms of organismal response to climate change (ORCC) with eco-evolutionary approaches to better manage the effects of a rapidly changing climate on earth's living systems. Specific areas of emphasis include but are not limited to: integrating physiology and genomics into the next generation of species distribution models; mechanistic understanding of plastic responses to climate change; functional genomics of organismal response to climate change; the role biological interactions play in organismal responses to climate change; and improving our ability to predict how organisms will respond to climate change and the consequences these responses will have across biological scales. Proposals to the ORCC Solicitation are encouraged that build on NSF's investment in growing convergence research by developing integrative, cross-disciplinary approaches that examine the organismal mechanisms that underlie adaptive and maladaptive responses to environmental factors associated with climate change, how these responses affect fitness in changing and/or novel climates, and the genetic and evolutionary processes through which these traits originate, persist, and are transmitted across generations.

Solicitation Number: NSF 22-515
Deadline: Proposals accepted anytime
Description: The Tectonics Program supports a broad range of field, laboratory, computational, and theoretical investigations aimed at understanding the deformation of the terrestrial continental lithosphere (i.e. above the lithosphere-asthenosphere boundary). The Program focuses on deformation processes and their tectonic drivers that operate at any depth within the continental lithosphere, on time-scales of decades/centuries (e.g. active tectonics) and longer, and at micro- to plate boundary/orogenic belt length-scales.

Facility and Instrumentation Request Process
Solicitation Number: NSF 21-611
Deadline: Anytime - Track 1 (Education & Outreach) & Track 2 (Single Facility Request)
Description: The Facility and Instrumentation Request Process (FIRP) solicitation describes the mechanism by which the research community can propose projects that require access to instrumentation and facilities sponsored by the Facilities for Atmospheric Research and Education (FARE) Program in the Division of Atmospheric and Geospace Sciences (AGS). FARE provides funding support to a variety of organizations to make specialized instrumentation and facilities available to the atmospheric science research community through the Lower Atmosphere Observing Facilities (LAOF) and the Community Instruments and Facilities (CIF) programs. FIRP allows for parallel evaluation of intellectual merit and broader impacts along with the feasibility of the proposed project. All research proposals and education and outreach proposals that require the use of FARE-sponsored assets must be submitted through this solicitation. PIs requesting the use of FARE-sponsored facilities for a scientific and/or educational project must follow the guidelines for submission in this solicitation. The FIRP solicitation offers three proposal submission tracks based on the type and purpose of the request: Track 1 - Education and Outreach. Track 2 - Single Facility Request. Track 3 - Field Campaigns. Preference for funding will be given to proposals submitted to programs in the Division of Atmospheric and Geospace Sciences in the Geosciences Directorate. If you are planning to submit a proposal to a program outside AGS, including NSF-wide or Directorate-wide solicitations and solicitations released under the NSF 10 Big Ideas, please contact the FARE program director to discuss the timelines, review process, and budget request for the use of FARE assets.

Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences (DMS/NIGMS)
Solicitation Number: NSF 22-600
Deadline: Sep 1 – Sep 18, annually
Description: The Division of Mathematical Sciences (DMS)in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF)and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams.

Computer and Information Science and Engineering (CISE) Research Initiation Initiative (CRII)
Solicitation Number: NSF 21-591
Deadline: Third Monday in September, Annually
Description: This solicitation encourages potentially transformative proposals in any area of CISE research from PIs who are in their first academic position post-PhD. The goal is for the PI to have the essential resources to launch their research career so that they may establish an independent research profile. For the purposes of this program, CISE defines "essential resources" as sufficient funds for 48 months of graduate student support, with more flexibility for faculty at Primarily Undergraduate Institutions (PUIs). (See Section IV: Additional Eligibility Information later in this document for details.) A Department Chair/Head Letter template [] must be used to affirm PI eligibility.

Computational and Data-Enabled Science and Engineering (CDS&E)
Solicitation Number: PD 22-8084
Deadline: Sep 1 – Nov 15, annually (deadlines vary by division)
Description: Large-scale simulations and the ability to accumulate massive amounts of data have revolutionized science and engineering. The goal of the CDS&E meta-program is to identify and capitalize on opportunities for major scientific and engineering breakthroughs through new computational and data-analysis approaches and best practices. The CDS&E meta-program supports projects that harness computation and data to advance knowledge and accelerate discovery above and beyond the goals of the participating individual programs. The intellectual drivers may be in an individual discipline, or they may cut across more than one discipline in various Divisions and Directorates. A CDS&E proposal should enable and/or utilize development and adaptation of advances in research and infrastructure in computational and data science.

Computational and Data-Enabled Science and Engineering in Mathematical and Statistical Sciences (CDS&E-MSS)
Solicitation Number: PD 22-8069
Deadline: proposals accepted anytime
Description: The CDS&E-MSS program accepts proposals that engage with the mathematical and statistical challenges presented by (1) the ever-expanding role of computational experimentation, modeling, and simulation on the one hand, and (2) the explosion in production and analysis of digital data from experimental and observational sources on the other. The goal of the program is to promote the creation and development of the next generation of mathematical and statistical software tools, and the theory underpinning those tools, that will be essential for addressing these challenges.

Robert Noyce Teacher Scholarship Program
Solicitation Number: NSF 21-578
Deadline: Last Tuesday in August, Annually
Description: The National Science Foundation Robert Noyce Teacher Scholarship Program (Noyce) invites innovative proposals that address the critical need for recruiting, preparing, and retaining highly effective elementary and secondary mathematics and science teachers and teacher leaders in high-need school districts. To achieve this goal, Noyce supports talented science, technology, engineering, and mathematics (STEM) undergraduate majors and professionals to become effective K-12 STEM teachers. It also supports experienced, exemplary K-12 STEM teachers to become teacher leaders in high-need school districts. In addition, Noyce supports research on the effectiveness and retention of K-12 STEM teachers in high-need school districts. Noyce offers four program tracks: Track 1: The Robert Noyce Teacher Scholarships and Stipends (S&S) Track, Track 2: The NSF Teaching Fellowships (TF) Track, Track 3: The NSF Master Teaching Fellowships (MTF) Track, and Track 4: The Noyce Research Track. In addition, Capacity Building proposals are accepted from proposers intending to develop a proposal in any of the program's tracks.

Geoscience Opportunities for Leadership in Diversity
Solicitation Number: PD-21-178Y
Deadline: Accepted anytime
Description: The GOLD Program supports the mission of achieving greater and more systemic diversity by creating a network of champions who can generate greater implementation of evidence-based best practices and resources to promote belonging, accessibility, justice, equity, diversity and inclusion (BAJEDI) throughout the geoscience education, research enterprise and workforce. Supported projects will research and develop the complex interplay of environmental context, personal traits, and motivating factors that

Education Programs in Atmospheric and Geospace Sciences
Solicitation Number: PD-21-7700
Deadline: Proposals Accepted Anytime
Description: GSEducation supports efforts to integrate atmospheric and geospace research and education via two main program areas, which are:

  1. Research Experiences for Undergraduates (REU) Site Program. This program provides funding to Universities andResearch Laboratories that allows them to offer summer internships to undergraduate students who would like to participate in atmospheric and/or geospace research efforts. Proposals may be submitted annually (August deadline).
  2. AGS Postdoctoral Fellowships:AGS awards 2-year Postdoctoral Fellowships to highly qualified investigators within 3 years of obtaining their PhD to carry out an integrated program of independent research and education. While the postdoc program is funded by core programs, the AGS Education program supports the cost of professional development for the fellows.

Conferences and Workshops in the Mathematical Sciences
Solicitation Number: NSF 21-541
Deadline: Proposals Accepted Anytime
Description: Conferences, workshops, and related events (including seasonal schools and international travel by groups) support research and training activities of the mathematical sciences community. Proposals for conferences, workshops, or conference-like activities may request funding of any amount and for durations of up to three years. Proposals under this solicitation must select "Conference" as the proposal type, and they must be submitted to the appropriate DMS programs in accordance with the lead-time requirements, submission windows, or deadlines specified on the program web page. See the DMS Programs page and click on the appropriate program for program-specific information.

Geomorphology and Land-use Dynamics (GLD)
Solicitation Number: NSF 21-547
Deadline: Proposals Accepted Anytime
Investigators can submit proposals to the Program at any time. Proposals submitted to other program solicitations such as CAREER, EAR Postdoctoral Fellowships, or Mid-Career Advancement (MCA) should continue to meet their respective deadlines.
Description: The GLD Program supports innovative fundamental research into processes that shape and modify earth's landscapes over a variety of length and time scales, with a focus on the Holocene. The program encourages research that quantitatively investigates the coupling and feedback among such processes, their rates, and their relative roles, especially in the contexts of variation in biologic, climatic, and tectonic influences and in light of changes due to human impacts. Such research may involve fieldwork, modeling, experimentation, theoretical development, or combinations thereof. GLD is particularly interested in increasing the participation of underrepresented groups in research and education such as women, persons with disabilities, and underrepresented minorities [1] [2], and those from geographically underrepresented areas in science, technology, engineering, and mathematics (STEM). Proposals submitted in response to this solicitation are strongly encouraged to involve PIs, co-PIs, postdoctoral researchers, students, and other personnel who are members of these groups. Proposers are also strongly encouraged to consider involving veterans of the U.S. Armed Forces as part of NSF’s broader effort to promote veteran involvement in STEM research and education.

Sustaining Infrastructure for Biological Research
Solicitation Number: NSF 21-503
Deadline: Proposals accepted anytime
Description: The Sustaining Infrastructure for Biological Research (Sustaining) Program supports the continued operation of existing research infrastructure that advances contemporary biology in any research area supported by the Directorate for Biological Sciences (BIO)at NSF. The Sustaining Program focuses primarily on sustaining critical research infrastructure that is cyberinfrastructure or biological living stocks and that is broadly applicable to a wide range of researchers. Projects are expected to ensure continued availability of existing, mature resources that will enable important science outcomes achieved by users representing a broad range of research supported by BIO and its collaborating organizations.

Transitions to Excellence in Molecular and Cellular Biosciences Research (Transitions)
Solicitation Number: NSF 21-508
Deadline: Accepted anytime
Description: The Division of Molecular and Cellular Biosciences (MCB) has developed a new opportunity to enable researchers with a strong track record of prior accomplishment to pursue a new avenue of research or inquiry. This funding mechanism is designed to facilitate and promote a PI’s ability to effectively adopt empowering technologies that might not be readily accessible in the PI’s current research environment or collaboration network. Transformative research likely spans disciplines and minimizing the practical barriers to doing so will strengthen research programs poised to make significant contributions. The award is intended to allow mid-career or later-stage researchers (Associate or Full Professor, or equivalent) to expand or make a transition in their research programs via a sabbatical leave or similar mechanism of professional development and then develop that research program in their own lab. This award will also enable the PI to acquire new scientific or technical expertise, facilitate the investigator’s competitiveness, and potentially lead to transformational impacts in molecular and cellular bioscience. The award would fund up to six months of PI salary during the first sabbatical or professional development year, followed by support for continued research for two subsequent years upon the PI’s return to normal academic duties. Requests for flexibility in the timing of the sabbatical or professional development year will be considered with appropriate justification. Please contact the cognizant program director for the solicitation. Through this solicitation MCB and NSF hope to develop a novel mechanism that will encourage investigators to expand and/or transition to new research areas aligned with MCB priorities, to increase retention of investigators in science, and to ensure a diverse scientific workforce that remains engaged in active research.

Infrastructure Capacity for Biological Research
Solicitation: NSF-23-580
Sponsored by: NSF
Deadline: Accepted anytime
Description: The Infrastructure Capacity for Biological Research (Capacity) Program supports the implementation of, scaling of, or major improvements to research tools, products, and services that advance contemporary biology in any research area supported by the Directorate forBiological Sciences at NSF. The Capacity Program focuses on building capacity in research infrastructure that is broadly applicable to a wide range of researchers in three programmatic areas: Cyberinfrastructure, Biological Collections, and Biological Field Stations and Marine Laboratories. This program will also accept proposals for planning activities or workshops to facilitate coordination that may be necessary in building capacity in infrastructure that meets the needs of a research community. Areas not included in this program are instrumentation (PIs should submit to the MRI program) and, projects that develop infrastructure for a specific research project, laboratory, or institution (PIs should submitted to the relevant BIO programs that would normally support that research). Projects are expected to produce quality products, result in important science outcomes that will be achieved by the users of the resource, be openly accessible to a broad scientific and education community, and serve a community of researchers beyond a single research team.

Infrastructure Innovation for Biological Research (IIBR)
Solicitation: NSF-23-578
Sponsored by: NSF
Deadline: Accepted anytime
Description: The Infrastructure Innovation for Biological Research Program (Innovation) supports research to design novel or greatly improved research tools and methods that advance contemporary biology in any research area supported by the Directorate forBiological Sciences at NSF. The Innovation Program focuses on research infrastructure that is broadly applicable to researchers in three programmatic areas: Bioinformatics, Instrumentation, and Research Methods. Infrastructure supported by this program is expected to advance biological understanding by improving scientists’ abilities to manipulate, control, analyze, or measure critical aspects of biological systems, which can be essential for addressing important fundamental research questions. Proposals submitted to these programmatic areas can do one of three things to advance or transform research in biology: develop novel infrastructure, significantly redesign existing infrastructure, or adapt existing infrastructure in novel ways. Projects are expected to have a significant application to one or more biological science questions and have the potential to be used by a community of researchers beyond a single research team.

Solicitation: PD 23-7236
Sponsored by: NSF
Deadline: Accepted anytime
Description: The goal of the Biophotonics program is to explore the research frontiers in photonics principles, engineering and technology that are relevant for critical problems in fields of medicine, biology and biotechnology. Fundamental engineering research and innovation in photonics is required to lay the foundations for new technologies beyond those that are mature and ready for application in medical diagnostics and therapies. Advances are needed in nanophotonics, optogenetics, contrast and targeting agents, ultra-thin probes, wide field imaging, and rapid biomarker screening. Low cost and minimally invasive medical diagnostics and therapies are key motivating application goals.

Arctic Research Opportunities
Solicitation: NSF 23-572
Sponsored by: NSF
Deadline: July 15, 2024
Description: The goal of this solicitation is to attract research proposals that advance a fundamental, process, and/or systems-level understanding of the Arctic's rapidly changing natural environment, social and cultural systems, and, where appropriate, to improve our capacity to project future change. The Arctic Sciences Section supports research focused on the Arctic region and its connectivity with lower latitudes.

Antarctic Research
Solicitation: NSF 21-567
Sponsored by: NSF
Deadline: Proposals Accepted Anytime
Description: The Antarctic Sciences Section (ANT) of the Office of Polar Programs (OPP) supports cutting-edge research that (1) expands fundamental knowledge of the Antarctic and the natural laboratory it represents across a range of disciplines, (2) improves understanding of interactions between the Antarctic and Southern Ocean region and Earth system, and (3) utilizes the unique characteristics of the Antarctic continent as an observing platform. The U.S. Antarctic Program (USAP) supports scientific research in Antarctica and the Southern Ocean with logistics provided by OPP’s Antarctic Infrastructure
and Logistics Section (AIL). Antarctic fieldwork is supported only for research that must be performed, or is best performed, in Antarctica. ANT encourages research, using existing samples, data, and models, that does not require fieldwork. ANT also encourages research that crosses and combines, disciplinary perspectives and approaches.

Electrochemical Systems
Solicitation: PD 23-7644
Sponsored by: NSF
Deadline: Continuously accepted
Description: The  Electrochemical Systems program is part of the Chemical Process Systems cluster, which also includes: 1) the  Catalysis program; 2) the  Interfacial Engineering program; and 3) the  Process Systems, Reaction Engineering, and Molecular Thermodynamics program.

The goal of the Electrochemical Systems program is to support fundamental engineering research that will enable innovative processes involving electro- or photochemistry for the sustainable production of electricity, fuels, and chemicals. Processes for sustainable energy and chemical production must be scalable, environmentally benign, reduce greenhouse gas production, and utilize renewable resources. Research projects that stress fundamental understanding of phenomena that directly impact key barriers to improved system or component-level performance (for example, energy efficiency, product yield, process intensification) are encouraged. Processes for energy storage should address fundamental research barriers for the applications of renewable electricity storage or for transport propulsion. For projects concerning energy storage materials, proposals should involve hypotheses that involve device or component performance characteristics that are tied to fundamental understanding of transport, kinetics, or thermodynamics. Advanced chemistries are encouraged.

Proposed research should be inspired by the need for economic and impactful conversion processes. All proposal project descriptions should address how the proposed work, if successful, will improve process realization and economic feasibility and compare the proposed work against current state of the art. Highly integrated multidisciplinary projects are encouraged.

Current topics of interest include:
Electrochemical Energy and Chemical Production Systems
Organic Photovoltaics Devices and Processing

Nanoscale Interactions
Solicitation Number: PD 23-1179
Deadline: No Deadline - Proposals for this program will be accepted throughout the year.
Description: The Nanoscale Interactions program is part of the Environmental Engineering and Sustainability cluster, which also includes: 1) the Environmental Engineering program; and 2) the Environmental Sustainability program.

The goal of the Nanoscale Interactions program is to support research to advance fundamental and quantitative understanding of the interactions of nanomaterials and nanosystems with biological and environmental media.

Materials of interest include one- to three-dimensional nanostructures, heterogeneous nano-bio hybrid assemblies, dendritic and micelle structures, quantum dots, and other nanoparticles. Such nanomaterials and systems frequently exhibit novel physical, chemical, photonic, electronic, and biological behavior as compared to the bulk scale. Collaborative and interdisciplinary proposals are encouraged.

Division of Environmental Biology (DEB)
Solicitation Number: NSF 22-541
Deadline: Accepted anytime
Description: The Division of Environmental Biology (DEB) Core Track supports research and training on evolutionary and ecological processes acting at the level of populations, species, communities, and ecosystems. DEB encourages research that elucidates fundamental principles that identify and explain the unity and diversity of life and its interactions with the environment over space and time. Research may incorporate field, laboratory, or collection-based approaches; observational or manipulative studies; synthesis activities; phylogenetic discovery projects; or theoretical approaches involving analytical, statistical, or computational modeling. Proposals should be submitted to the core clusters (Ecosystem Sciences, Evolutionary Processes, Population and Community Ecology, and Systematics and Biodiversity Sciences).

Petrology and Geochemistry (CH)
Solicitation Number: NSF 22-560
Deadline: Proposals Accepted Anytime
Description: The Petrology and Geochemistry Program supports basic research on the formation of planet Earth, including its accretion, early differentiation, and subsequent petrologic and geochemical modification via igneous and metamorphic processes. Proposals in this program generally address the petrology and high-temperature geochemistry of igneous and metamorphic rocks (including mantle samples), mineral physics, economic geology, and volcanology. Proposals that are focused on the development of analytical tools, theoretical and computational models, and experimental techniques for applications by the igneous and metamorphic petrology, and high temperature geochemistry and geochronology communities are also invited.

Division of Integrative Organismal Systems Core Programs
Solicitation Number: NSF 24-546
Deadline: Accepted Anytime
Description: The Division of Integrative Organismal Systems (IOS) Core Programs Track supports research aimed at understanding why organisms are structured the way they are and function as they do. Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, nervous system development, structure, modification, function, and evolution; biomechanics and functional morphology, physiological processes, symbioses and microbial interactions, interactions of organisms with biotic and abiotic environments, plant and animal genomics, and animal behavior. The IntBIO Track invites submission of collaborative proposals to tackle bold questions in biology that require an integrated approach to make substantive progress. Integrative biological research spans sub-disciplines and incorporates cutting-edge methods, tools, and concepts from each to produce groundbreaking biological discovery that is synergistic, such that the sum is greater than the parts.

Foundational Research in Robotics
Solicitation Number: PD-20-144Y
Deadline: Proposals accepted anytime
Description: The Foundational Research in Robotics (Robotics) program supports research on robotic systems that exhibit significant levels of both computational capability and physical complexity. For the purposes of this program, a robot is defined as intelligence embodied in an engineered construct, with the ability to process information, sense, and move within or substantially alter its working environment. Here intelligence includes a broad class of methods that enable a robot to solve problems or make contextually appropriate decisions. Research is welcomed that considers inextricably interwoven questions of intelligence, computation, and embodiment. Projects may also focus on a distinct aspect of intelligence, computation, or embodiment, as long as the proposed research is clearly justified in the context of a class of robots.

Re-entry to Active Research Program (RARE)
Solicitation Number: NSF-20-586
Sponsored by: NSF
Deadline: Anytime
Description: The Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) and the Division of Chemistry (CHE) are conducting a Re-entry to Active Research (RARE) program to reengage, retrain, and broaden participation within the academic workforce. The primary objective of the RARE program is to catalyze the advancement along the academic tenure-track of highly meritorious individuals who are returning from a hiatus from active research. By providing re-entry points to active academic research, the RARE program will reinvest in the nation’s most highly trained scientists and engineers, while broadening participation and increasing diversity of experience. A RARE research proposal must describe potentially transformative research that falls within the scope of participating CBET or CHE programs.

Dear Colleague Letter: Advancing education for the future AI workforce (EducateAI)
Solicitation Number: NSF 24-025
Deadline: NA
Description: The Directorates for Computer and Information Science and Engineering (CISE) and STEM Education (EDU) are launching the EducateAI initiative to support educators to make state-of-the-art, inclusive AI educational experiences available nationwide. With this Dear Colleague Letter (DCL), EDU and CISE encourage the submission of novel and high impact proposals that advance inclusive computing education that prepares preK-12 and undergraduate students for the AI workforce. This EducateAI DCL seeks to support: professional learning opportunities & communities; inclusive AI educational resources (curricula, tools, data sources, assessments, etc.); and educational infrastructure needed to support AI education across institutions; and build upon/contribute to research on broadening participation to better understand and inform efforts to support students from groups historically underrepresented in computing; and research and development needed to make state-of-the-art, inclusive AI education available to all students in preK-12 schools, 2-year colleges, and 4-year colleges and universities.

Dear Colleague Letter: Improving Undergraduate STEM Education – Adaptation, Implementation, and Dissemination (IUSE-AID)
Solicitation Number: NSF 24-026
Deadline: NA
Description: This DCL encourages STEM education communities to submit proposals to the Directorate for STEM Education’s Improving Undergraduate STEM Education (IUSE:EDU) program (NSF 23-510) that focus on Adaptation and Implementation, and/or Dissemination of proven teaching strategies and learning materials reflecting advances in what is known about undergraduate STEM teaching and learning. Proposals that develop faculty expertise, implement educational innovations, adapt existing educational innovations for specific teaching and learning environments, and disseminate teaching and learning innovations beyond the scale of the efforts that created them are encouraged. Potential project emphases: Adaptation and Implementation of Existing Instructional Strategies; Dissemination of Existing Instructional Strategies.

Dear Colleague Letter: Tool Development for Molecular and Cell Biology (Tools4Cells)
Solicitation Number: 23-121
Deadline: NA
Description: This DCL encourages submission of proposals to develop novel tools and methods that improve scientists’ abilities to measure, analyze, manipulate, or control critical aspects of cellular properties and functions in order to continue to push boundaries and open new avenues of inquiry in molecular and cellular biosciences.

Dear Colleague Letter: NSF and the Romanian Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI) Lead Agency Opportunity in the Mathematical Sciences
Solicitation Number: NSF 23-132
Deadline: Varies by division
Description: The Division of Mathematical Sciences (DMS) within the Mathematical & Physical Sciences Directorate (MPS) of the National Science Foundation (NSF) and the Romanian Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI) have created a partnership to support international collaboration under the NSF-UEFISCDI Lead Agency Opportunity in the Mathematical Sciences. The goal of this activity is to promote collaborative research within the mathematical sciences by reducing barriers to conducting research with international collaborators. The NSF-UEFISCDI Lead Agency Opportunity allows U.S. and Romanian researchers to submit a single collaborative proposal that will undergo a single merit review process through NSF as the lead agency.

Dear Colleague Letter: Interdisciplinary REU Sites at the Intersection of Computing and Communication Foundations and Mathematics and Statistics
Solicitation Number: NSF 23-082
Deadline: Varies by division
Description: REU projects involve students in meaningful ways in ongoing research programs or in research projects specifically designed for the REU program. The REU Sites program aims to provide appropriate and valuable educational experiences for undergraduate students through participation in research. Interdisciplinary REU sites offer the opportunity to bring together researchers and students from different disciplines to enable cross-fertilization and initiate new research directions. Interdisciplinary REU sites can also help to grow a new generation of students with unique skills to tackle important research problems of interest to both disciplines. The purpose of this Dear Colleague Letter (DCL) is to invite the submission of interdisciplinary REU Sites proposals that explore high impact topics at the intersection of Computing and Communication Foundations and Mathematics and Statistics to the REU program.

Dear Colleague Letter: High School Student Research Assistantships (MPS-High) Funding to Broaden Participation in the Mathematical and Physical Sciences
Solicitation Number: NSF 22-041
Deadline: Continuously accepted (AST, CHE, DMR, DMS, PHY, OMA)
Description: Inviting requests which foster interest in the pursuit of studies in the Mathematical and Physical Sciences; and broaden participation of high school students who are in groups that have been traditionally underrepresented and under-served in STEM fields.

Dear Colleague Letter: Bioinspired Design Collaborations to Accelerate the Discovery-Translation Process (BioDesign)
Solicitation Number: NSF 23-055
Deadline: Continuously accepted (BIO, ENG, TIP)
Description: Bioinspired design is the process by which investigators take inspiration from the natural world (from molecular and cellular to organismal and higher scales) to discover general principles about biological and/or engineering systems and use them to inform and generate new design directions for engineered systems or products. Investigators formulate how these principles and phenomena can be converted into specific, high-impact solutions (such as human-built devices, materials, products, processes, systems, and systems of systems) for problems faced by society. Bridging the gaps between foundational and use-inspired research as well as the translation of research results to practice requires transdisciplinary collaboration. To encourage such collaborations, this DCL will support productive transdisciplinary teams that work together to (1) test hypotheses about the functioning of living things that are of interest to biologists and engineers; (2) create an iterative process that generates ongoing feedback between the workflows of foundational and use-inspired research in order to design a device, machine, algorithm, and/or a workflow that solves a practical problem; and (3) develop prototypes based on these activities as part of a process of exploring pathways to larger societal and economic benefits.

Dear Colleague Letter: ANR - NSF/MCB/PHY Lead Agency Opportunity at the Molecular and Cellular Biosciences - Physics Interface
Solicitation Number: NSF 22-129
Deadline: no deadline
Description: The lead agency opportunity allows U.S. and French researchers to submit a single proposal describing a project involving U.S. and French researchers that will undergo a single review process by the lead agency, on behalf of NSF/MCB, NSF/PHY and ANR. The emergence, evolution, dynamics, and function of self-organized cellular systems stem from the interaction of biological components and the environment to yield robust, resilient, and adaptive living systems. Through this DCL, NSF and ANR seek proposals that use multidisciplinary approaches that emphasize quantitative, predictive and theory driven science aimed at understanding mechanisms underlying these essential life processes at the molecular, subcellular, and cellular scales. We are seeking proposals that integrate approaches from theoretical and experimental physics and biology to develop testable and quantitative understanding of biological questions. Projects providing innovative methodological or conceptual approaches to a biological question together with a strong theoretical physics component are strongly encouraged. Projects that leverage unique resources and capabilities of partners in the U.S. and France will be given priority.

Dear Colleague Letter: Supplements for Access to Semiconductor Fabrication (ASF)
Solicitation Number: NSF 22-113
Deadline: no deadline
Description: With this Dear Colleague Letter (DCL), the National Science Foundation's Directorate for Engineering (ENG), the Directorate for Computer and Information Science and Engineering (CISE), and the Directorate for Mathematical and Physical Sciences (MPS) wish to notify the community of a new supplement program that will support access to semiconductor fabrication for principal investigators (PIs) of currently active awards in ENG, CISE, and Divisions of Materials Research (DMR) and Chemistry (CHE) in MPS. These supplemental funding requests are specifically targeted to support fabrication of research devices and systems through standard semiconductor fabrication facilities. The design of semiconductor integrated circuits and systems has become easier than ever before, given the wide and relatively affordable availability of industry-standard electronic design automation (EDA) tools, a recently emerging slate of open-source EDA tools, and a growing set of intellectual property (IP) in the form of design infrastructure. However, fabrication of these designs has become less frequent for a variety of reasons. This ASF supplement DCL is designed to address one aspect of this challenge through supplemental funding specifically to support fabrication of research devices and systems through standard semiconductor fabrication facilities.

Dear Colleague Letter: CHE FY22 International Supplement
Solicitation Number: NSF 22-070
Deadline: May 1 (annually)
Description: The Division of Chemistry is inviting requests for supplemental funding from its existing awardees who may wish to add a new, or strengthen an existing, international dimension of their research supported by an award from the Division, when an international collaboration advances the field of chemistry and enhances the U.S. investigator's own research and/or education objectives. Principal Investigators supported by NSF Division of Chemistry research awards are advised to consult with their cognizant NSF program director prior to submitting a supplemental funding request.

Dear Colleague Letter: Mathematical and Scientific Foundations of Deep Learning and Related Areas (MoDL+)
Solicitation Number: NSF 22-023
Deadline: varies by division
Description: This Dear Colleague Letter (DCL) is to encourage the submission of proposals from interdisciplinary teams comprised of computer scientists, electrical engineers, mathematicians and statisticians, and social, behavioral, and economic scientists to address the most challenging theoretical and foundational questions in machine learning. The National Science Foundation (NSF) Directorates for Computer and Information Science and Engineering (CISE), Engineering (ENG), Mathematical and Physical Sciences (MPS), and Social, Behavioral and Economic Sciences (SBE) promote interdisciplinary research in Mathematical and Scientific Foundations of Deep Learning and related areas (MoDL+). Deep learning and other related modern machine learning technologies have met with impressive empirical success, fueling fundamental scientific discoveries, and transforming numerous application domains of artificial intelligence. The incomplete theoretical understanding of the field, however, impedes the use of machine learning techniques by a wider range of participants. Confronting this incomplete understanding of the mechanisms underlying the successes and failures of machine learning is essential to overcoming its limitations and expanding its applicability.

Dear Colleague Letter: NSF-DFG Lead Agency Opportunity in Molecular and Cellular Biology
Solicitation Number: NA
Deadline: Proposals accepted continuously
Description: Recognizing the importance of international collaborations in promoting scientific discoveries, the US National Science Foundation (NSF) and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) have signed a Memorandum of Understanding (MOU) on research cooperation. The MOU provides an overarching framework to encourage collaboration between US and German research communities and sets out the principles by which jointly supported activities might be developed. The MOU provides for a Lead Agency Opportunity whereby proposals may be submitted to either NSF or DFG. To facilitate the support of collaborative work between US researchers and their German counterparts, the Division of Molecular and Cellular Bioscience (BIO/MCB) at NSF and the Division of Molecular and Organismal Biology and Agriculture (MOBA) at DFG are pleased to announce a Lead Agency Opportunity in the area of Molecular and Cell Biology (NSF-DFG MolCellBio). The goal of this Opportunity is to help reduce some of the current barriers to working internationally. This Lead Agency Opportunity allows US and German researchers to develop and submit a single proposal to either NSF or DFG describing a project involving US and German researchers that will undergo a single review process by the designated Lead Agency. US and German collaborators are invited to submit joint proposals in the areas covered by NSF's BIO/MCB and DFG's review board 201 "Basic Research in Biology and Medicine." The proposals should focus on basic research at a molecular, subcellular or cellular level, including theoretical approaches.

Dear Colleague Letter: Models for Uncovering Rules and Unexpected Phenomena in Biological Systems (MODULUS)
Solicitation Number: NSF 21-069
Deadline: proposals accepted anytime
Description: Proposals funded through this DCL are anticipated to cultivate innovative modes of collaboration among researchers working at the interface of mathematics and molecular and cellular biology, with an emphasis on systems-scale integration. Each proposal submitted in response to this DCL should address a current state-of-the-research challenge and describe a strategy for formative integration of mathematical and biological understanding to address the challenge. In addition, the proposal should describe the unique interdisciplinary training opportunity for graduate students and postdoctoral researchers working on the project.

NEW Advanced Research Projects Agency for Health
Programs of interest:
Resilient Systems Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
Solicitation: ARPA-H-SOL-24-103
Application Deadline: March 14, 2025
Description: This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSO’s interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.

Health Science Futures: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
Solicitation: ARPA-H-SOL-24-104
Application Deadline:  March 14, 2025
Description: This ISO seeks solution summaries and proposal submissions for projects that fall within the general scope of the ARPA-H Health Science Futures (HSF) mission office. HSF expands what is technically possible by developing approaches that will remove the scientific and technological limitations that stymie progress towards the healthcare of the future. HSF supports cutting-edge, often disease-agnostic research programs that have the potential for translational real-world change.

Scalable Solutions Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
Solicitation: ARPA-H-SOL-24-105
Application Deadline: March 14, 2025
Description: This ISO seeks solution summaries and proposals for projects that fall within the general scope of the ARPA-H Scalable Solutions mission office. SSO expands what is technically possible by developing approaches that will leverage an interdisciplinary approach and collaborative networks to address challenges of geography, distribution, manufacturing, data and information, thereby improving health care access and affordability. In the United States, many communities and remote areas lack access to timely and quality health care, which leads to disparities in health outcomes for those populations. Bottlenecks during the manufacturing processes of products and health technologies also lead to delays and limited availability, preventing effective distribution of health care solutions to areas of need, especially in emergencies.

Proactive Health Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
Solicitation: ARPA-H-SOL-24-106
Application Deadline: March 14, 2025
Description: The Proactive Health Office (PHO) at ARPA-H is seeking solutions to improve the healthspan and health outcomes of Americans prior to the onset of disease and/or the development of diminished quality of life from illness. Specifically, PHO hypothesizes that 1) population-level improvements in access to and uptake of disease prevention and wellness-promoting behaviors and 2) development of novel early-detection methods and prophylactic interventions could drastically improve the health of American throughout their lives, and 3) that system level innovations are required for delivery of proactive health effectively.

NEW NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional)
Solicitation: RFA-RM-24-004
Deadline: September 03, 2024
Description: The NIH Director’s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIH’s Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications in all topics relevant to the broad mission of NIH are welcome in all topic areas relevant to the broad mission of NIH, including, but not limited to, behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH.

Early-stage Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed)
Solicitation: PAR-23-236
Deadline: Standard due dates through Jan 25, 2026. LOI (strongly encouraged) due 60 days prior to the application due date.
Description: This program supports the development of early-stage or new data repositories or knowledgebases that could be valuable for the biomedical research community. The overall goal is to support pilot activities that demonstrate the need and potential impact of the data resource. The NOFO will also support transitioning resources that are currently supported as investigator-initiated research efforts into quality controlled, standards-based resources that address governance, and efficiency of operations. Efforts to consolidate existing data repositories or independent knowledgebases are also in scope for this NOFO.

Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)
Solicitation: PAR-23-237
Deadline: Standard due dates through Jan 25, 2026. LOI (strongly encouraged) due 60 days prior to the application due date.
Description: This program supports established biomedical data resources that have demonstrated impact and have potential for continued benefit to the mission of one or more of the NIH Institutes and Centers participating in this announcement. Applications funded under this NOFO for established data resources must already exist, address the needs of the targeted biomedical research community, document scientific impact they have had thus far, and have potential for continued benefit to the community served. Applications appropriate for this NOFO can support data resources for biomedical research, spanning biological scales including molecular, cellular, tissue, organism, and/or population data, as well as social and behavioral data. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of the resource operations. An application should distinctly support either a data repository or a knowledgebase. Resources that desire to support both should submit separate applications to ensure their proper review per the distinct review criteria.

Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
Solicitation: PAR-23-281
Deadline: Standard due dates through June 5, 2026
Description: The National Cancer Institute (NCI) invites applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research. The NCI, through this NOFO encourages submission of projects devoted to demonstrating that mammalian models, including organoids, tumoroids and cell models, used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patient benefit.

Maximizing Investigators' Research Award (R35 - Clinical Trial Optional)
Solicitation: PAR-22-180
Deadline: May 16, 2024; January 16, 2025; May 16, 2025
Description: Supporting fundamental research by funding individual projects has a number of consequences that reduce the efficiency and effectiveness of the biomedical research enterprise in the U.S. To address these issues and increase the efficiency and efficacy of grant funding, the NIGMS Maximizing Investigators' Research Award (MIRA) is a single grant to provide support for the NIGMS-relevant program of research in an investigator's laboratory. For this FOA, the "program of research" is defined as a collection of projects in an investigator's laboratory that are within the mission of NIGMS.

Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI) (R35 - Clinical Trial Optional)
Solicitation: PAR-23-145
Deadline: October 03, 2024; February 03, 2025; October 03, 2025; February 03, 2026
Description: The Maximizing Investigators' Research Award provides support for a program of research in an early stage investigator's laboratory that falls within the mission of NIGMS. For the purpose of this NOFO, a program of research is a collection of projects in the investigator's lab that are relevant to the mission of NIGMS. The goal of MIRA is to increase the efficiency and efficacy of NIGMS funding.

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
Solicitation: PA-23-272
Deadline: Aug 08, 2024; Dec 08, 2024; Apr 08, 2025; Aug 08, 2025
Description: The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) award is to enable promising predoctoral students to obtain individualized, mentored research training from outstanding faculty sponsors while conducting dissertation research in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The proposed mentored research training must reflect the candidate’s dissertation research project and is expected to clearly enhance the individual’s potential to develop into a productive, independent research scientist.

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
Solicitation: PAR-22-080
Deadline: June 3, 2024
Description: The Shared Instrument Grant (SIG) Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-priced, specialized, commercially available instruments or integrated instrumentation system. The minimum award is $50,000. There is no maximum price limit for the instrument; however, the maximum award is $600,000. Instruments supported include, but are not limited to: X-ray diffractometers, mass spectrometers, nuclear magnetic resonance spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.

High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)
Solicitation: PAR-22-079
Deadline: June 3, 2024
Description: The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. The minimum award is $600,001. There is no maximum price limit for the instrument; however, the maximum award is $2,000,000. Instruments supported include, but are not limited to, X-ray diffractometers, high throughput robotic screening systems, mass spectrometers, nuclear magnetic resonance spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.

NCI Small Grants Program for Cancer Research for Years 2023, 2024, and 2025 (NCI Omnibus) (R03 Clinical Trial Optional)
Solicitation: PAR-23-058
Deadline: June 20, 2024; Oct 17, 2024; Feb 24, 2025; June 20, 2025; Oct 17, 2025
Description: The R03 small grant mechanism supports discrete, well-defined projects in an y area of cancer research that realistically can be completed in 2 years and that require limited levels of funding. Examples of the types of projects that the R03 grant mechanism include, but are not limited to, the following: Pilot or feasibility studies; Secondary analysis of existing data; Small, self-contained research projects; Development of research methodology; and Development of new research technology.

Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)
Solicitation: PAR-24-022
Deadline: Standard due dates through October 16, 2025
Description: This Trailblazer Award is an opportunity for NIH-defined New and Early Stage Investigators to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high risk-high impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Importantly, applicants must propose research approaches for which there are minimal or no preliminary data. A distinct feature for this FOA is that no preliminary data are required, expected, or encouraged. However, if available, minimal preliminary data are allowed.

Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R24 Clinical Trials Not Allowed)
Solicitation: PAR-23-039
Deadline: Standard due dates through May 25, 2025
Description: The Office of Research Infrastructure Programs (ORIP) encourages resource-related research grant applications aimed at developing broadly applicable technologies, tools, and resources for validating animal models and enhancing rigor, reproducibility, and translatability of animal research. Proposed studies, models, resources, or technologies submitted under this Funding Opportunity Announcement (FOA) must either address research interests of multiple NIH Institutes and Centers (ICs), explore multiple organ systems, or be applicable to diseases and processes that impact multiple organ systems in order to align with ORIP’s NIH-wide mission and programs. Applications should aim to enhance the rigor, reproducibility, and translatability of animal research through the development of technologies, tools, and resources that have significant impact across a broad range of research areas using animal models. Applications must demonstrate how the proposed resources and technologies impact rigor and reproducibility of animal studies.

Imaging, Biomarkers and Digital Pathomics for the Early Detection of Premetastatic Cancer and Precancerous Lesions Associated with Lethal Phenotypes (R01 Clinical Trial Optional)
Solicitation: PAR-22-131
Deadline: NIH standard due dates through June 5, 2025
Description: This FOA supports the development of state-of-the-art projects that integrate imaging, biomarkers, digital pathomics, glycomics, metabolomics, other omic information and/or meta data obtained from platforms including but not limited to lower resolution diagnostic acquisitions and systemic biomarker results to high resolution single-cell analytics / imaging applied to the characterization of heterogeneous cell populations within tumor for improving current approaches for: (1) the early detection of organ confined premetastatic aggressive cancer, and, (2) identifying precancerous lesions associated with the development of a subsequent lethal phenotype. This FOA specifically attempts to address and improve diagnostic uncertainty in clinical decisions by improving detection sensitivity and specificity of integrated multiparametric platforms.

Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)
Solicitation: PAR-21-294
Sponsored by: NIH-Dept of Health and Human Services
Deadline: Sep 07, 2024
Description: The purpose of this Funding Opportunity Announcement (FOA) is to invite research grant applications (R01) for the development and use of current and emerging molecular imaging methods to gain fundamental insights into cancer inflammation in vivo. The motivation for this initiative is that much of current imaging research into the role of inflammation in cancer is largely based on in vitro and ex vivo methods with limited utilization of imaging approaches that could lead to significant new insights relevant to dynamic cancer and inflammation interactions. Utilization of molecular imaging probes in pre-clinical and clinical investigations for precise temporal resolution at the molecular and cellular level are valuable approaches for identification and characterization of in vivo inflammatory cellular physiology in cancers and of molecular changes in response to treatment. This FOA encourages applications that focus on developing integrated imaging approaches to interrogate the role of inflammation in cancer through strong cross-field collaboration between cancer basic science researchers and imaging scientists. These collaborations are expected to advance science and understanding of cancer inflammation interactions.

Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required)
Solicitation: PAR-21-039
Sponsored by: NIH
Deadline: January 26, 2024 (NOT-OD-23-175)
Description: The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Funding Opportunity Announcement (FOA) must not include preliminary data. Applications must include a separate attachment describing the change in research direction.

Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)
Solicitation: PAR-19-369
Sponsored by: NIH
Deadline: Standard Due Dates Apply: February 16, June 16, October 16
Description: This funding opportunity announcement (FOA) encourages innovative research to develop, characterize, and improve animal models, biological materials, and novel technologies to better understand human health and disease. This FOA also seeks projects aimed at improving the diagnosis and control of diseases that interfere with animal use for biomedical research. The proposed project must have broad application to multiple NIH Institutes or Centers (ICs) to align with the Office of Research Infrastructure Programs’ (ORIP) trans-NIH mission. The proposed studies must explore multiple body systems or evaluate diseases that impact multiple body systems. Applications that develop models focused on a specific disease or area of research, or only propose studies primarily relevant to a single NIH IC will be considered not acceptable to this FOA.

Glenn W. Bailey Foundation: STEM Program Grants
Sponsor: Glenn W. Bailey Foundation
Deadline: LOIs are accepted at any time
Description: The Foundation offers awards to support postsecondary STEM programming, including opportunities to expand on current programs or seed money to create new programs. Funding can support many activities and initiatives such as club activities, career management counselors, showcases, research projects, camps, tech talks, student clubs and organizations, lecture series, and professor continuing education programs.

Targeted Grants in Mathematics and Physical Sciences
Sponsor: Simons Foundation
Deadline: Continuously accepted (LOI required)
Description: The program is intended to support high-risk theoretical mathematics, physics and computer science projects of exceptional promise and scientific importance on a case-by-case basis.

American Chemical Society Petroleum Research Fund
Sponsor: American Chemical Society
Deadline: March 7, 2025
Description: The Petroleum Research Fund supports fundamental research directly related to petroleum or fossil fuels. ACS PRF grants are intended as seed money, to enable an investigator to initiate a new research direction. The investigator should not have published or received financial support from another funding agency for the proposed research. Proposals must be for fundamental research in “the petroleum field,” which is defined in our founding document as “petroleum, natural gas, coal, shale, tar sands and like materials.” ACS PRF funds two programs: New Directions and Doctoral New Investigator.

Damon Runyon Fellowship Award
Sponsor: Damon Runyon Cancer Research Foundation
Deadline: August 15, 2024
Description: The Foundation encourages all theoretical and experimental research relevant to the study of cancer and the search for cancer causes, mechanisms, therapies and prevention. Candidates must apply for the fellowship under the guidance of a Sponsor—a scientist (tenured, tenure-track or equivalent position) capable of providing mentorship to the Fellow.

Kleberg Foundation - Medical Research
Sponsor: Robert J. Kleberg Jr. and Helen C. Kleberg Foundation
Deadline: March 31; September 30
Description: The Foundation is seeking highly innovative and groundbreaking medical research proposals from top tier institutions in both basic biological and applied research that will have the greatest impact on scientific knowledge and human health. Proposals should be distinctive and novel in their approaches, question the prevailing paradigm, and lead to advancement of knowledge in the field.

Whitehall Foundation Grant Programs
Sponsor: Whitehall Foundation
Deadline: LOIs: Jan 15, Apr 15, Oct 1. Full applications: Jun 1, Sep 1, Feb 15
Description: The Whitehall Foundation aims to support scholarly research in the life sciences that are not heavily supported by federal agencies or other foundations with specialized missions. The foundation emphasizes the support of young scientists at the beginning of their careers and productive senior scientists who wish to move into new fields of interest. The Foundation is currently interested in basic research in neurobiology, defined as follows: Invertebrate and vertebrate (excluding clinical) neurobiology, specifically investigations of neural mechanisms involved in sensory, motor, and other complex functions of the whole organism as these relate to behavior. The overall goal should be to better understand behavioral output or brain mechanisms of behavior. The Foundation does not support research focused primarily on disease(s) unless it will also provide insights into normal functioning.

National Centers Planning Award
Sponsor: University of Houston
Deadline: Applications accepted through August 31, 2024, or until the funds are exhausted
Description: President Khator’s Research Preeminence: 50-in-5 initiative calls for a doubling of our national centers from the current five centers to ten centers over the next five years. Applying for a center grant is a major effort. In recognition of this effort, the Division of Research (DOR) is offering internal planning grants to prepare for a center grant application. The funding is intended to provide up to 14 months of support to teams of researchers led by a University of Houston (UH) faculty member to prepare for the submission of a proposal to a targeted funding opportunity.