Profile: Yuen-Sum (Vincent) Lau

Lau, Y.-S. (2005) Progressive neurodegeneration in the chronic MPTP/probenecid model of Parkinson’s disease.  In: Parkinson’s Disease (Eds. M. Ebadi and R. Pfeiffer). CRC Press, Boca Raton, FL, pp. 109-115.

Garris, D.R., Garris B.L. Novikova, L., Lau, Y.-S. (2005) Structural, metabolic and endocrine analysis of the diabetes (db/db) hypogonadal Syndrome: Relationship to hypophyseal hypercytolipidemia.  Cell & Tissue Research 319: 501-512.

Lau,Y.-S., Roels, C., Novikova, L. (2005) MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact. Neuroscience Research 52: 371-378.

Welch, W.J., Mendonca, M., Blau, J., Karber, A., Dennehy, K., Patel, K., Lau, Y.-S., Jose, P., Wilcox, C.S. (2005) Antihypertensive response to prolonged tempol in the spontaneously hypertensive rat.  Kidney International 68: 179-187.

Novikova, L., Garris, B.L., Garris, D.R., Lau, Y-S. (2006) Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson’s disease.  Neuroscience 140: 67-76.

Al-Jarrah, M., Pothakos, K., Novikova, L., Smirnova, I.V., Kurz, M.J., Stehno-Bittel, L., Lau, Y.-S. (2007) Endurance exercise promotes cardiorespiratory rehabilitation without neurorestoration in the chronic mouse model of Parkinsonism with severe neurodegeneration. Neuroscience 149: 28-37.

Kurz, M.J., Pothakos, K., Jamaluddin, S., Scott-Pandorf, M., Arellano, C., Lau, Y.-S. (2007) A chronic mouse model of Parkinson's disease has a reduced gait pattern certainty.  Neuroscience Lett. 429: 39-42.

Banday, A.A., Lau, Y.-S., Lokhandwala, M.F. (2008) Oxidative stress causes renal dopamine D1 receptor dysfunction and salt-sensitive hypertension in Sprague-Dawley rats. Hypertension 51: 367-375.

Leasure, J.L., Giddabasappa, A., Chaney, S., Johnson, J.E., Pothakos, K., Lau, Y.-S., Fox, DA (2008) Low-level human equivalent gestational lead exposure produces gender-specific motor and coordination abnormalities and late-onset obesity in year-old mice. Environmental Health Perspectives 116: 355-361.

Li, H., Armando, I., Yu, P., Escano, C., Mueller, S.C., Asico, L., Pascua, A., Lu, Q., Wang, X., Villar, V.A., Jones, J.E., Wang, Z., Periasamy, A., Lau, Y.-S., Soares-da-Silva, P., Creswell, K., Guillemette, G., Sibley, D.R., Eisner, G., Felder, R.A., Jose, P.A. (2008) Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells. J. Clin. Invest. 118: 2180-2189.

Ahmad, S.O., Park J.H., Stenho-Bittel, L., Lau, Y.-S. (2009) Effects of endurance exercise on ventral tegmental area neurons in the chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and probenecid-treated mice. Neuroscience Lett. 450: 102-105.

Pothakos, K., Kurz, M.J., Lau, Y.-S. (2009) Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson’s disease with severe neurodegeneration.  BMC Neuroscience 10: 6 (pp 1-14).

Barber-Singh, J., Seo, B.B., Nakamaru-Ogiso, E., Lau, Y.-S., Matsuno-Yagi, A., Yagi, T. (2009) Neuroprotective effect of long-term NDI1 gene expression in a chronic mouse model of Parkinson disorder.  Rejuvenation Res. 12: 259-267.

Escano, C.S., Armando, I., Wang, X., Asico, L., Pascua, A., Yang, Y., Wang, Z., Lau, Y.-S., Jose, P.A. (2009) Renal dopaminergic defect in C57BL/6J mice.  Am J Physiol, Regul Integr Comp Physiol. 297: R1660-1669.

Patki, G., Che, Y., Lau, Y.-S. (2009) Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson’s disease.  Frontiers in Aging Neuroscience, 1: 3 (pp 1-9).