People


Dr. Yoonjung Park

Assistant Professor

Office Number: 104F GAR
Phone: 713-743-9350
Fax: 713-743-9860

Email: ypark10@uh.edu

Mailing Address:
3855 Holman St., Rm 104 Garrison
Houston, TX 77204-6015

Download Curriculum Vitae

Research Interests

My research efforts focus on 1) Investigate the role of physical activity and exercise training in preventing or ameliorating vascular (endothelial) dysfunction in pathophysiologic conditions such as obesity, type 2 diabetes, ischemic heart disease, hypertension, aging (Alzheimer), microgravity, etc. in animal and human subjects, and 2) Elucidating the mechanisms in which vascular function is altered by the sequelae of the diseases and physical activity/exercise training at the molecular, cellular, and intact tissue levels (isolated intact microvessels).

Recent Publications and Research Activity

Park Y, Prisby RB, Lesniewski LA, Donato AJ, Delp MD. Effects of aging and exercise training on Angiotensin 11-induced vasoconstrcition of rat skeletal muscle arterioles, J Appl Phsiol., Oct;113(7):1091-100. 2012

Park Y, Booth FW, LeeS, Laye MJ, and Zhang C. Physical Activity Opposes Coronary Vascular Dysfunction Induced during High Fat Feeding in Mice. J Physiol (Lond). Sep; 1 ;590(Pt 17):4255-68. 2012

Lee S, Park Y, Zhang C. Exercise Training Prevents Coronary Endothelial Dysfunction in Type 2 Diabetic Mice. Am. J. Biomed. Sci 3(4): 241-252.2011

Lee S, Park Y, Dellsperger KC, Zhang C. Exercise training improves endothelial function via adiponectin-dependent and independent pathways in type 2 diabetic mice. Am J Physiol Heart Circ Physiol. Aug;301(2):H306-14. 2011

Lee S, Park Y, Zuidema MY, Hannink M, Zhang, C. Effects of interventions on oxidative stress and inflammation of cardiovascular diseases. World Journal of Cardiology (invited review), January 26; 3(1 ): 18-24. 2011

Park Y, Yang J, Zhang H, Chen X and Zhang C. Role of PAR2 in the Regulation of TN F-ainduced Endothelial Dysfunction in Type 2 Diabetic mice. Basic Res Cardiol. Jan;106(1):111-23. 2011

Zhang H, Park Y, Liu Y and Zhang C. Coronary and Aortic Endothelial Function Affected by Feedback between Adiponectin and TNF-a in Type 2 Diabetic Mice. Arterioscler Thromb Vase Bioi. 2010 Nov;30(11):2156-63

Yang J, Park Y, Zhang H, Gao X, Wilson E, Zimmer W, Abbott L and Zhang C. Role of MCP-1 in Tumor Necrosis Factor alpha-induced Endothelial Dysfunction in Type 2 Diabetic Mice. Am J Physiol Heart Circ Physiol. 297(4):H1208-16. 2009

Yang J, Park Y, Zhang H, Xu X, Laine GA, Dellsperger KC and Zhang C (*Co-first authors). Feed-forward Signaling of TNF-a. and NFKB via IKKI3 Pathway Induces Insulin Resistance and Coronary Arteriolar Dysfunction in Type 2 Diabetic Mice. Am J Physiol Heart Circ Physiol. 296(6):H1850-8, 2009

Park Y, Wu J, Zhang H, Wang Y and Zhang C. Vascular dysfunction in type 2 diabetes: emerging targets for therapy. Expert Rev Cardiovasc Ther. Mar;7(3):209-13, 2009

Zhang H, Park Y, Wu J, Chen X, LeeS, Yang J, Dellsperger KC and Zhang C. The Role of TNF-alpha in Vascular Dysfunction. Clin Sci (Lond). 116 (3): 219-230, 2009

Park Y, Capobianco S, Gao X, Falck JR, Dellsperger KC and Zhang C. Role of EDHF in type 2 diabetes-induced endothelial dysfunction. Am J Physiol Heart Circ Physiol. 295(5):H1982-8, 2008

Zhang C, Park Y, Picchi A and Potter BJ. Maturation-induced Endothelial Dysfunction via Vascular Inflammation in Diabetic Mice. Basic Res Cardiol. 103(5):407-16. 2008

Gao X, Park Y, Capobianco S, Yang J, Zhang H, Picchi A and Zhang c.ยท Role of TNF alpha in Prediabetic Metabolic Syndrome Induced Endothelial Dysfunction. 81 World Congress for MICROCIRCULATION (Ed. Julian H Lombard). MEDIMOND S.r.l., International Proceedings., H815R9145: P179-185. 2007

Saitoh S, Kiyooka T, Rogers PA, Dick GM, Rocic P, Swafford A, Viswanathan C, Park Y, Zhang C, Chilian WM. Redox-Dependent Coronary Metabolic Dilation. Am J Physiol Heart Circ Physiol. 293(6):H3720-5, 2007

Gao X, Xu X, Belmadani S, Park Y, Tang Z, Feldman AM, Chilian WM and Zhang C. TNFalpha Contributes to Endothelial Dysfunction by Up-regulation Arginase in 1/R Injury. Arterioscler Thromb Vase Bioi. 27(6):1269-75, 2007.

Starnes JW, Taylor RP, Park Y. Exercise improves postischemic function in aging hearts. Am J Physiol Heart Circ Physiol. 285(1 ):H347-H351, 2003

Park YJ, Lee HJ, Kim YK, Jin YS. The effects of exercise training on MV02 and QTc interval in obese women. Korean J. of Sports Medicine. 17(1) 188-196, 1999 (In Korean)

Kang HJ, Chung ST, Park YJ, Kim MH, Jin YS. The effect of Physical Exercise on V02 max and Blood Lipid Profile in NIDDM. Korean J. of Sports Medicine. 16(2): 313-319, 1998 (In Korean)

Education

B.A. in Physical Education at Seoul National University, 1997

M.A. in Clinical Exercise Physiology at Seoul National University, 1999

M.A. in Exercise Physiology at University of Texas at Austin, 2003

Ph.D. in Exercise Physiology at Texas A&M University, 2006

Post-doc in Internal Medicine at Division of Cardiovascular Medicine, University of Missouri, 2010