MINXUE ZHENG

Objective

Education

Experience and Accomplishments

Honors and Awards

Professional Memberships

Publications

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OBJECTIVE

Seeking a highly challenging scientist position in chemical or pharmaceutical industry that requires multi-field proficiency

EDUCATION

1993 - 1997 Ph.D., Organic Chemistry - University of Houston, Houston, TX GPA: 3.7

1992 - 1993 Ph.D. candidate in Physical Chemistry - University of Houston. GPA: 4.0

1990 - 1991 M.S., High Energy Physics - University of Massachusetts, Dartmouth, MA GPA: 3.9

1986 - 1990 B.S.,Theoretical Physics - Zhejiang University, Hangzhou, Zhejiang, P.R.China GPA: 3.6

EXPERIENCE AND ACCOMPLISHMENTS

1993 to Present - Reseach Assistant, W.M.KECK NMR Center, University of Houston.

• Structure, dynamics and stability of nucleic acids: Dicovered and solved the first high resolustion three dimensional strucures of an unusual DNA triplet repest in solution using complete matrix relaxation and restrained moleculardynamics calculations;
• Solid phrase chemical synthesis and ChemRobotics;
• HPLC and other chromatographic separation methods;
• multi-dimensional (NOESY, ROESY, COSY, TOCSY) and pulse field gradient NMR experiments on Bruker 600 MHz magnet and spectrometer.

1992 to 1993 - Research Assistant, Institute for Molecular Design, University of Houston, Houston TX

• Development and coding of "UHBD" (part of the MSI modeling package Quanta ) to study difusion and protein-ligand interactions.

1991 to 1992 - Physics Associate, E852, BrookHeaven National Laboratory, Upuon, LongIsland

• Computer aided design and optimize of lead scintillator detector by Monte - Carlo simulations;
• Complex optical and electronic devices with computer controlled AD-DA interface.
• Automated data collect and analysis system

1990 to 1991 - Research Assistant, Synchrotron Radiation Laboratory, Academia Sinica.

• Biophysis research : experiment and computer simulation the effect of synchrotron radiaton in biological system.

HONORS and AWARDS

1996 	The Bayer Inc., Foundation Graduate Scholarship Award, Chemistry Departmental
	Award, University of Houston.

1996	Graduate student travel award of the XVIIth International Conferenceon Magnetic
	Resonance in Biological System (Keystone, Colorado).

1996	Welch Gradute Fellowship award, University of Houston.
	
1995 	First place ($400 award) of research poster competition (collaborated with
 	fellow graduate students), Department of Chemistry, University of Houston.

1995	Welch Scholarship award, Department of Chemistry, University of Houston.

1986	Award winner in the First Chinese National Physics Student Competition, P.R. 
	CHINA.

1986	Award winner in the First Chinese National Computer Programming Competition,
	P.R. CHINA.

PROFESSIONAL MEMBERSHIP

1996 - Present American Association for Advancement of Science
1996 - Present American Chemical Society
1996 - Present BioMedNet

PUBLICATIONS

1. Zheng, M., Huang, X., Smith, K., Yang, X., and Gao, X. (1996) High folding propensity and duplex formation of single standed DNA triplet repeats related to hereditary neurodegenerative diseases. J. Mol. Bio. in press
2. Zheng, M. , and Gao, X. (1996) Parrallel and antiparallel duplex formation by triplet repeat GAC in biological solution. in preparation. 
3. Zheng, M. , and Gao, X. (1996) High resolution structure of the duplex formed by triplet repeat (GAC)3 in solution. in preparation.
4. Gao, X., Huang, X., Smith, G. K., Zhang, M. , and Liu, H. (1995) A new antiparallel duplex Motif of DNA CCG repeats that is stabilized by extrahelical. J. Am. Chem. Soc. 117, 8883-8884.
5. Wang, W., Liang, C. Zheng, M. , and Gao, X. (1995) Selective acylation of N-(2-Phosphonoethyl) ethylenediamine phosphonates. Ttrahedron Letters 36, 1181-1184.
6. Gao, X., Smith, G.K., Huang, X., and Zheng, M. (1995) Unusual solution structure unveiled by NMR studies of single-stranded DNA triplet repeats. J. Cellular Biochemistry Supplement 21B , 58

Last Update: November 9, 1996