University of Houston Molecular Medicine & Experimental Therapeutics: Craft LAB UH-MMET

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Reyes-Alcaraz A, Qasim H, Merlinsky E, Fox G, Islam T, Medina B, Schwartz RJ, Craft JW Jr, McConnell BK. A Small Molecule That In Vitro Neutralizes Infection of SARS-CoV-2 and Its Most Infectious Variants, Delta, and Omicron. Biomedicines. 2023 Mar 15;11(3). doi: 10.3390/biomedicines11030916. PubMed PMID: 36979895; PubMed Central PMCID: PMC10046252.

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Hickman A, Koetsier J, Kurtanich T, Nielsen MC, Winn G, Wang Y, Bentebibel SE, Shi L, Punt S, Williams L, Haymaker C, Chesson CB, Fa'ak F, Dominguez AL, Jones R, Kuiatse I, Caivano AR, Khounlo S, Warier ND, Marathi U, Market RV, Biediger RJ, Craft JW Jr, Hwu P, Davies MA, Woodside DG, Vanderslice P, Diab A, Overwijk WW, Hailemichael Y. LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade. J Clin Invest . 2022 Jul 1;132(13). doi: 10.1172/JCI154152. PubMed PMID: 35552271; PubMed Central PMCID: PMC9246385.

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St. Hill LR, Tran H, Chinwangso P, Lee HJ, Marquez MD, Craft Jr J, Lee T. Antifouling Studies of Unsymmetrical Oligo(ethylene glycol) Spiroalkanedithiol Self-Assembled Monolayers. Micro. 2021 September; 1(1).

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St Hill LR, Craft JW Jr, Chinwangso P, Tran HV, Marquez MD, Lee TR. Antifouling Coatings Generated from Unsymmetrical Partially Fluorinated Spiroalkanedithiols. ACS Appl Bio Mater. 2021 Feb 15;4(2):1563-1572. doi: 10.1021/acsabm.0c01409. Epub 2021 Feb 1. PubMed PMID: 35006665; PubMed Central PMCID: PMC8812961.

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Bakthavatsalam D, Craft JW Jr, Kazansky A, Nguyen N, Bae G, Caivano AR, Gundlach CW 4th, Aslam A, Ali S, Gupta S, Lin SY, Parthiban HD, Vanderslice P, Stephan CC, Woodside DG. Identification of Inhibitors of Integrin Cytoplasmic Domain Interactions With Syk. Front Immunol. 2020;11:575085. doi: 10.3389/fimmu.2020.575085. eCollection 2020. PubMed PMID: 33488575; PubMed Central PMCID: PMC7819857.

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Abbasgholizadeh R, Zhang H, Craft JW Jr, Bryan RM Jr, Bark SJ, Briggs JM, Fox RO, Agarkov A, Zimmer WE, Gilbertson SR, Schwartz RJ. Discovery of vascular Rho kinase (ROCK) inhibitory peptides. Exp Biol Med (Maywood). 2019 Aug;244(11):940-951. doi: 10.1177/1535370219849581. Epub 2019 May 27. PubMed PMID: 31132884; PubMed Central PMCID: PMC6690139.

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Kurakula K, Koenis DS, Herzik MA Jr, Liu Y, Craft JW Jr, van Loenen PB, Vos M, Tran MK, Versteeg HH, Goumans MTH, Ruf W, de Vries CJM, Şen M. Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity. Haematologica. 2018 Jun;103(6):1073-1082. doi: 10.3324/haematol.2017.183087. Epub 2018 Mar 15. PubMed PMID: 29545340; PubMed Central PMCID: PMC6058786.

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Woodside DG, Tanifum EA, Ghaghada KB, Biediger RJ, Caivano AR, Starosolski ZA, Khounlo S, Bhayana S, Abbasi S, Craft JW Jr, Maxwell DS, Patel C, Stupin IV, Bakthavatsalam D, Market RV, Willerson JT, Dixon RAF, Vanderslice P, Annapragada AV. Magnetic Resonance Imaging of Atherosclerotic Plaque at Clinically Relevant Field Strengths (1T) by Targeting the Integrin α4β1. Sci Rep. 2018 Feb 27;8(1):3733. doi: 10.1038/s41598-018-21893-x. PubMed PMID: 29487319; PubMed Central PMCID: PMC5829217.

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Cherubin P, Garcia MC, Curtis D, Britt CB, Craft JW Jr, Burress H, Berndt C, Reddy S, Guyette J, Zheng T, Huo Q, Quiñones B, Briggs JM, Teter K. Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds. PLoS One. 2016;11(11):e0166477. doi: 10.1371/journal.pone.0166477. eCollection 2016. PubMed PMID: 27829022; PubMed Central PMCID: PMC5102367.

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Craft JW Jr, Shen TW, Brier LM, Briggs JM. Biophysical characteristics of cholera toxin and Escherichia coli heat-labile enterotoxin structure and chemistry lead to differential toxicity. J Phys Chem B. 2015 Jan 22;119(3):1048-61. doi: 10.1021/jp506509c. Epub 2014 Nov 5. PubMed PMID: 25322200.

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Craft JW Jr, Zhang H, Charendoff MN, Mindrebo JT, Schwartz RJ, Briggs JM. Associations between the Rho kinase-1 catalytic and PH domain regulatory unit. J Mol Graph Model. 2013 Nov;46:74-82. doi: 10.1016/j.jmgm.2013.09.009. Epub 2013 Oct 4. PubMed PMID: 24149321.

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Rababa'h A, Craft JW Jr, Wijaya CS, Atrooz F, Fan Q, Singh S, Guillory AN, Katsonis P, Lichtarge O, McConnell BK. Protein kinase A and phosphodiesterase-4D3 binding to coding polymorphisms of cardiac muscle anchoring protein (mAKAP). J Mol Biol. 2013 Sep 23;425(18):3277-88. doi: 10.1016/j.jmb.2013.06.014. Epub 2013 Jun 25. PubMed PMID: 23806656; PubMed Central PMCID: PMC3808176.

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Anastasio NC, Gilbertson SR, Bubar MJ, Agarkov A, Stutz SJ, Jeng Y, Bremer NM, Smith TD, Fox RG, Swinford SE, Seitz PK, Charendoff MN, Craft JW Jr, Laezza FM, Watson CS, Briggs JM, Cunningham KA. Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior. J Neurosci. 2013 Jan 23;33(4):1615-30. doi: 10.1523/JNEUROSCI.2656-12.2013. PubMed PMID: 23345234; PubMed Central PMCID: PMC3711763.

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Carreño R, Brown WS, Li D, Hernandez JA, Wang Y, Kim TK, Craft JW Jr, Komanduri KV, Radvanyi LG, Hwu P, Molldrem JJ, Legge GB, McIntyre BW, Ma Q. 2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1. J Biol Chem. 2010 Oct 22;285(43):32860-32868. doi: 10.1074/jbc.M110.111591. Epub 2010 Aug 19. PubMed PMID: 20724473; PubMed Central PMCID: PMC2963386.

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Sen M, Herzik M, Craft JW, Creath AL, Agrawal S, Ruf W, Legge GB. Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. Open Spectrosc J. 2009 Jan 1;3:58-64. doi: 10.2174/1874383800903010058. PubMed PMID: 20076769; PubMed Central PMCID: PMC2805860.

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Ampapathi RS, Creath AL, Lou DI, Craft JW Jr, Blanke SR, Legge GB. Order-disorder-order transitions mediate the activation of cholera toxin. J Mol Biol. 2008 Mar 28;377(3):748-60. doi: 10.1016/j.jmb.2007.12.075. Epub 2008 Jan 5. PubMed PMID: 18272180; PubMed Central PMCID: PMC2441595.

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Craft JW Jr, Legge GB. An AMBER/DYANA/MOLMOL phosphorylated amino acid library set and incorporation into NMR structure calculations. J Biomol NMR. 2005 Sep;33(1):15-24. doi: 10.1007/s10858-005-1199-0. PubMed PMID: 16222554.