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Profile: Sanket Patel

Sanket Patel
Sanket Patel, Ph.D.
Research Assistant Professor of Pharmacology

Health 2
University of Houston College of Pharmacy
4849 Calhoun Road, Room 5004A
Houston, TX 77204-5037

713-743-3868 
snpatel5@central.uh.edu

Education

St. John's University, New York, Ph.D. Pharmaceutical Sciences ('14) and M.S. Pharmaceutical Sciences ('09)

L.M. College of Pharmacy, Gujarat University, Ahmedabad, INDIA, Bachelor of Pharmacy, 2004

St. John's University Research Fellowship, 2013-14

Academic & Research Interests

My research interest is focused towards understanding the molecular mechanisms of angiotensin-II type 2 receptor activation in combating oxidative stress, adiposity, inflammation and kidney dysfunction. Moreover, I am interested in understanding the molecular and signaling mechanisms that regulate receptor dimerization of angiotensin-II receptors and receptor Mas.

Awards & Honors

  • Biotex Labratories Junior Scientist Award in Immunology 2019 by Association of Scientists of Indian Origin in America at the 8th National Meeting on April 10
  • The Kidney Council New Investigator Award 2016 by American Heart Association

Selected Publications

Original Research

Fatima N, Patel SN, Hussain T (2021). Angiotensin II Type 2 Receptor: A Target for Protection Against Hypertension, Metabolic Dysfunction, and Organ Remodeling. Hypertension. 77(6):1845-1856.

Patel SN, Fatima N, Ali R, Hussain T (2020). Emerging Role of Angiotensin AT2 Receptor in Anti-Inflammation: An Update. Curr Pharm Des. 26(4):492-500.

Patel SN and Hussain T (2020). Synergism between angiotensin receptors ligands: role of angiotensin‐(1‐7) in modulating AT2R agonist response on nitric oxide in kidney cells. Pharmacol Res Perspect 8(6):e00667

Patel SN, Dhande IS, Gray EA, Ali Q, Hussain T (2019). Prevention of lipopolysaccharide-induced CD11b+ immune cell infiltration in the kidney: role of AT2 receptors. Biosci Rep 39(5):1-13

Nag S, Patel SN, Mani S, Hussain T (2019). Role of angiotensin type 2 receptor in improving lipid metabolism and preventing adiposity. Mol Cell Biochem 461(1-2):195-204

Patel SN, Ali Q, Steckelings UM, Hussain T (2017). Angiotensin II type 2 receptor and receptor Mas are functionally interdependent in obese Zucker rat kidney. Hypertension 70(4):831-838

Patel SN, Ali Q, Hussain T (2016). Angiotensin II type 2-receptor agonist C21 reduces proteinuria and oxidative stress in kidney of high-salt fed obese Zucker rats. Hypertension 67(5):906-915

Patel SN, Pandya KG, Clark GJ, Parikh MC, Lau-Cam CA (2016). Comparison of taurine and pantoyltaurine as antioxidants in vitro and in the central nervous system of diabetic rats. Exp Toxicol Pathol 68(2-3):103-112

Ali Q, Patel SN, Hussain T (2015). Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol 308(12):F1379-F1385

Bhavsar TM, Patel SN, Lau-Cam CA (2010). Protective action of taurine, given as a pretreatment or as a posttreatment, against endotoxin-induced acute lung inflammation in hamsters. J Biomed Sci 17(Suppl 1):S19

Bhavsar TM, Cantor JO, Patel SN, Lau-Cam CA (2009). Attenuating effect of taurine on lipopolysaccharide-induced acute lung injury in hamsters. Pharmacol Res 60(5):418-428

Invited Reviews

Patel SN, Fatima N, Ali R, Hussain T (2020). Emerging role of angiotensin AT2 receptor in anti-inflammation: an update. Curr Pharm Des 26(4):492-500

Patel SN, Hussain T (2018). Dimerization of AT2 and Mas receptors in the control of blood pressure. Curr Hypertens Rep 20(5):41

Invited Editorial Commentaries

Patel SN, Tahir Hussain (2018). Role of angiotensin type 2 receptor in maintaining sodium-potassium balance. Hypertension 71(4):653-655

Patel SN, Narayan P, Goldberg ID, Naaz F, Hussain T, Ali Q (2018). Kidney appreciates stable blood pressure. Am J Hypertens 31(5):532-533

Book Chapters

Patel SN, Lau-Cam CA (2019). Modification by ethanol and taurine, singly and in combination, of changes in indices of renal dysfunction caused by diabetes in rats. In: Taurine 11 (pp. 369-380). Springer, Singapore.

Patel SN, Lau-Cam CA (2017). The effect of taurine and its immediate homologs on diabetes-induced oxidative stress in the brain and spinal cord of rats. In: Taurine 10 (pp. 337-351). Springer, Dordrecht.

Patel SN, Parikh M, Lau-Cam CA (2015). Impact of light ethanol intake and of taurine, separately and together, on pathways of glucose metabolism in the kidney of diabetic rats. In: Taurine 9 (pp. 279-303). Springer, Cham.

Parikh MC, Patel SN, Shen Y, Lau-Cam CA (2015). Role of taurine on the actions of alcohol against systemic and cardiac biochemical changes in the diabetic rat. In: Taurine 9 (pp. 313-338). Springer, Cham.

Additional Training & Certifications

Focus on Peer Review, a Nature Masterclasses online course by Springer Nature

Principles of Clinical Pharmacology Course Year 2017-2018, Nature Institute of Health Clinical Center

Collaborative Institutional Training Initiative (CITI) Certificate for Animal Research

New York Academy of Sciences After-school Science Technology Engineering Math (STEM) Mentor, Science Education Fellowship Program

Professional Service

Academic Editor (Medicine) and reviewer of several internationally recognized peer-reviewed journals (33)