In Partial Fulfillment of the Requirements for the Degree of
Doctor of Philosohpy
Will defend her dissertation proposal
Breast reconstruction is an important surgical component for many women undergoing breast cancer treatment. The purpose of breast reconstruction is to recreate a breast form that is satisfying to the patient, facilitating her psychosocial adjustment to living as a breast cancer survivor. Breast reconstruction is usually completed in a multi-step process which can take up to a year or longer. The goal of this project is to develop algorithms to monitor and quantify changes in local breast morphology during the reconstruction process.
This project will encompass the following three topics:
For the first step, we have developed a semi-automated rigid registration algorithm. The approach relies on the assumption that while the soft tissues of the patient's body may change over time, the skeleton is relatively stable. Thus the transformation of skeletal frame can be treated as being rigid. Selecting points with reference to the skeletal frame and maximizing the correspondence between these points can then achieve 3D image registration. This algorithm is robust to discrepancies in fiducial point selection (sternal notch and umbilicus) of about 2 cm.
In future, we propose to develop an automated registration algorithm of 3D torso images in order to avoid operator bias in the semi-automated method. Finally, we will design and develop algorithms for breast data extraction and quantitative analysis of local breast morphology changes.
Date: Friday, December 14, 2012
Time: 2:00 PM
Faculty, students, and the general public are invited.
Advisor: Prof. Fatima Merchant and Prof. Shishir Shah