Design, synthesis, and use of novel biomimetic ultrasmall paramagnetic iron oxide nanoparticles with dual bioresponsive elements capable of selectively targeting tumor cells.
Selectivity to tumor cells. Dual bioresponsive elements. Stealth MR probes that are targeted. Dual functioning – imaging & pathophysiological information. Contrast agents in the market – Feridex, Ferumoxil, Ferumoxitran, magnetophages, (SPIO)-anti-c-MET, RGDS-USPIO
Future uses: Ultimodal system for drug and gene delivery in addition to imaging
Oncological imaging, pharmaceutical industry for combination imaging and therapy.