"Houston Scholars has given me the opportunity to explore my area of study through computational research, allowing me to further my knowledge and my career."
Major: Honors Biomedical Sciences
Houston Scholars Project:
Effect of Various Inhibitors on Enzymatic Activity of Fructose-1,6-Bisphosphatase
Advisor: Dr. James Briggs
Skyler Howell is a sophomore, Mathematical Biology major conducting computational research under the mentorship of Dr. James Briggs in the department of Biology and Biochemistry at the University of Houston. Specifically, Skyler is working to identify inhibitors that selectively target energy production and metabolism in metastatic cancer cells. Skyler is using computational tools such as Visual Molecular Dynamics and Autodock to simulate inhibitor-enzyme interactions and binding. Skyler’s in silico findings will be tested experimentally in the laboratory of Dr. Zhang Weihua, also here at the University of Houston.
Future Direction: Upon gradation, Skyler would like to enter a joint MD/PhD program and ultimately wants to conduct research as a clinician scientist in the biotechnology industry.